T1604

Tiratricol (3,3',5-Triiodothyroacetic acid) is a metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.

Mepazine (Pecazine) is a potent and selective inhibitor of MALT1, inhibiting GSTMALT1 full length and GSTMALT1 325-760 with IC50s of 0.83 μM and 0.42 μM, respectively. Mepazine enhances apoptosis and impacts cell viability.

Methotrexate metabolite (DAMPA) (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic agent and immunosuppressant.

Metaldehyde (Metacetaldehyde) is an agriculturally used molluscicide that induces DNA fragmentation in cells.

Mepixanox is an analeptic drug. It is used for treating respiratory and cardiorespiratory insufficiency.

Metaproterenol also has anti-inflammatory activity. Metaproterenol is a direct-acting sympathomimetic and a β2-adrenergic receptor (β2AR) agonist (IC50: 68 nM).

Methoprene (ZR-515) is a juvenile hormone (JH) mimic and a biological pesticide. Methoprene acts as an insect growth regulator interfering with the lifecycles of insects and preventing insects from reaching maturity or reproducing.

Methyl propionate-PEG12, a PEG-based PROTAC linker, is utilized for the synthesis of PROTACs[1].

Methylamino-PEG1-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Methylamino-PEG1-Boc is a PEG-based linker for PROTACs, which connects two essential ligands essential for forming PROTAC molecules, enabling selective protein degradation through the ubiquitin-proteasome system within cells.

Methylamino-PEG2-acid is a PEG-based linker for PROTACs, joining two essential ligands and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.