pbr — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T22782	FGIN-1-27		Others
	high affinity agonist of the translocator protein		Others
T1308	Orphenadrine hydrochloride	Mebedrol,Mephenamin	Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor
	Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T6618	Orphenadrine Citrate	Flexon,Flexoject,Banflex	AChR , iGluR
	Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects.		AChR , iGluR
T60157	PBRM1-BD2-IN-8		Epigenetic Reader Domain
	PBRM1-BD2-IN-8 (compound 34) is a potent PBRM1 Bromodomain inhibitor (PBRM1-BD2 Kd=4.4 μM, PBRM1-BD2 IC50=0.16 μM; PBRM1-BD5 Kd=25 μM). PBRM1-BD2-IN-8 shows anti-cancer activity.		Epigenetic Reader Domain
T60158	PBRM1-BD2-IN-3		Epigenetic Reader Domain
	PBRM1-BD2-IN-3 (compound 12) is a potent inhibitor of PBRM1-BD2, exhibiting an IC50 value of 1.1 μM, and is utilized in anticancer research.		Epigenetic Reader Domain
T60156	PBRM1-BD2-IN-2		Epigenetic Reader Domain
	PBRM1-BD2-IN-2, a selective and cell-active inhibitor of the polybromo-1 (PBRM1) bromodomain, exhibits binding affinity and inhibitory activity specifically targeting the PBRM1-BD2 domain, with Kd and IC50 values of 9.3 ...		Epigenetic Reader Domain
T60159	PBRM1-BD2-IN-5		Epigenetic Reader Domain
	PBRM1-BD2-IN-5 is a potent inhibitor of the PBRM1 Bromodomain, demonstrating dissociation constant (Kd) values of 1.5 μM and 3.9 μM for PBRM1-BD2 and PBRM1-BD5, respectively, and boasts an inhibitory concentration 50 (IC...		Epigenetic Reader Domain
T60155	PBRM1-BD2-IN-7		Epigenetic Reader Domain
	PBRM1-BD2-IN-7, a selective and cell-active inhibitor targeting the polybromo-1 (PBRM1) bromodomain, demonstrates inhibitory efficacy against PBRM1-BD2 with an IC50 value of 0.29 μM. This compound is utilized in cancer r...		Epigenetic Reader Domain
T24836	ß-pBrPh-Glc	Beta-pBrPh-Glc,ßpBrPhGlc,p-Bromophenyl-beta-D-glucopyranoside,p-Bromophenyl-ß-D-glucopyranoside	Antioxidant
	ß-pBrPh-Glc (ßpBrPhGlc) is an inhibitor of ice recrystallization, controlling the growth of extracellular ice and inhibiting the recrystallization of intracellular ice. ß-pBrPh-Glc may be used as a cryopreservative , pos...		Antioxidant
T78076	PBR28		Others
	PBR28, a TSPO modulator, holds potential for preventative research in Pulmonary Arterial Hypertension (PAH) and is instrumental in brain positron emission tomography (PET) imaging studies through its capacity for radioac...		Others
T72843	PBRM1-BD2-IN-6
	PBRM1-BD2-IN-6, a potent inhibitor of the PBRM1 bromodomain, exhibits an IC50 value of 0.22 µM and demonstrates antiproliferative activity. It holds potential for research in PBRM1-dependent cancer treatment.
T70980	PBRM
	PBRM is the first selective, potent, non-estrogenic, irreversible inhibitor of 17β-HSD1.
T72841	PBRM1-BD2-IN-1
	PBRM1-BD2-IN-1 is a selective and cell-active inhibitor of the polybromo-1 (PBRM1) bromodomain, displaying binding affinity and inhibitory efficacy with Kd and IC50 values of 0.7 μM and 0.2 μM, respectively. This compoun...
T3173	DAA-1106	DAA1106	Others , GABA Receptor
	DAA-1106 is a potent and selective ligand for peripheral benzodiazepine receptor (PBR), acting as a potent and selective agonist at the peripheral benzodiazepine receptor.		Others , GABA Receptor