hpv — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP1595	Human Papillomavirus (HPV) E7 protein (49-57)	Human Papillomavirus (HPV) E7 protein 49-57
	Human Papillomavirus (HPV) E7 protein (49-57) is the H-2d-restricted human papillomavirus (HPV) E749-57 epitope.
T8350	TPCK		Proteasome
	TPCK is an irreversible inhibitor of chymotrypsin-like proteases that affect cell proliferation, apoptosis, and tumorigenesis		Proteasome
TN4417	Larixyl acetate		Others
	Larixyl acetate is a bioactive chemical.		Others
T12711	Retro-2 cycl	RN 1-001	Virus Protease
	Retro-2 cycl is a dihydroquinazolinone (DHQZ) retrograde trafficking inhibitor. Retro-2 cycl (RN 1-001) inhibits JCPyV and HPV16 pseudovirus(IC50s of 54 μM and 160 μM, respectively),with antiviral agent.		Virus Protease
T1583	Vorinostat	MK0683,suberoylanilide hydroxamic acid,SAHA	Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy
	Vorinostat (SAHA) is a pan-histone deacetylase (HDAC) inhibitor (IC50=10 nM) with inhibitory activity against HDAC1/2/3/6/7/11. Vorinostat has antitumor activity, induces cell differentiation, blocks the cell cycle and i...		Apoptosis , Mitophagy , Virus Protease , HDAC , Autophagy
TP1554	HPV16 E7 (86-93)
	This is amino acids 86 to 93 fragment of the human papilloma virus (HPV) type 16 oncoprotein E7. This HPV16-encoded peptide has very high affinity of binding to the HLA-A*0201 molecule.This immunogenic fragment may be us...
TP1515	HPV16-E711-20 epitope
	HPV16-E711-20 epitope is a well-known HLA-A0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV*16 E7 protein that shows high-affinity binding to HLA-A2 in vitro.
TP1525	HPV16 E7 (86-93) (TFA)(160212-93-1,free)	HPV16 E7 (86-93) (TFA)
	HPV16 E7 (86-93) TFA is a human leukocyte antigen (HLA)-A2.1 restricted HPV16 E7-derived peptide.
TP1554L	HPV16 E7 (86-93) acetate	HPV16 E7 (86-93) acetate(160212-93-1 Free base)	Others
	HPV16 E7 (86-93) acetate is a derived peptide of human leukocyte antigen A2.1 restricted HPV16 E7 with immunogenic property in cervical carcinomas.		Others
T60544	HPV18-IN-1
	HPV18-IN-1 (Compound H1) is a potent HPV18 inhibitor that prevents cervical cancer cells from premature cell procession and abnormal proliferation. HPV18-IN-1 supresses E7-Rb-E2F cellular pathway and DNA methylation with...
T76015	HPV16 E7 (86-93) (TFA)
	HPV16 E7 (86-93) TFA, a peptide derived from HPV16 E7, is restricted by human leukocyte antigen (HLA)-A2.1 and exhibits immunogenic properties in cervical carcinomas [1] [2].
T25466	GS-9191	GS 9191	DNA/RNA Synthesis
	GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetrates the skin and is metabolized in the epithelium to an ac...		DNA/RNA Synthesis
T77423	Lirilumab	ONO-4483,IPH2102	Virus Protease
	Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-depende...		Virus Protease
T17228	Sabizabulin	ABI-231,VERU-111	Microtubule Associated
	Sabizabulin (ABI-231) is an effective and orally bioavailable inhibitor of α and β tubulin against panels of melanoma and prostate cancer cell lines. Sabizabulin inhibits tumor growth and metastatic phenotypes of cervica...		Microtubule Associated
T28534	RH02007	CCG 40788,RH-02007,CCG40788,CCG-40788,RH 02007
	RH02007 is an inhibitor of the human papillomavirus (HPV) E6 oncoprotein.
T71941	Lig3
	Lig3 is an inhibitor against high-risk strains of human papillomavirus (HPV) E6 oncoprotein.
T76960	Verpasep caltespen
	Verpasep caltespen (HspE7), a recombinant fusion protein, originates from the Mycobacterium bovis Calmette-Guérin heat shock protein 65 (Hsp65) and is covalently bonded at its C-terminal end to the E7 protein of HPV16. T...
T72241	Teslexivir hydrochloride	BTA074 hydrochloride ; AP 611074 hydrochloride,BTA074 hydrochloride,AP 611074 hydrochloride
	Teslexivir hydrochloride (BTA074) is a potent antiviral agent that serves as a selective inhibitor of the E1 and E2 viral proteins' interaction, a crucial step for DNA replication and viral production in Human Papilloma ...
T76336	Astodrimer
	Astodrimer (SPL7013 free base), a large (3-4 nm, ~16.5 kDa) and negatively charged dendrimer, possesses potent virucidal capabilities. Exhibiting antiviral and virucidal activities, it effectively targets a wide array of...
T79941	Antimycin A2c		Apoptosis
	Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces cas...		Apoptosis