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Results for "

912545-86-9

" in TargetMol Product Catalog.
  • Inhibitors & Agonists
    1
    TargetMol | All_Pathways
  • SAG
    Smoothened Agonist
    T1779912545-86-9
    SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
    • $41
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    TargetMol | Citations Cited
Other Forms of Products
  • SAG-D3
    TMID-1049
    SAG-D3 is the deuterated form of SAG. As a potent agonist of the Smoothened (Smo) receptor, SAG (T1779) exhibits an EC50 of 3 nM and a Kd of 59 nM.
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  • SAG hydrochloride (912545-86-9(free base))
    Smoothened Agonist HCl
    T42112095432-58-7
    SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
    • $47
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    TargetMol | Citations Cited
  • (Rac)-SAG
    T85362364590-63-6
    (Rac)-SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC₅₀ = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].
    • Inquiry Price
    10-14 weeks
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  • SAG dihydrochloride
    T404652702366-44-5
    SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
    • $48
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