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Results for "

75 se

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    280
    TargetMol | Inhibitors_Agonists
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    2
    TargetMol | Compound_Libraries
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    TargetMol | Inhibitors_Agonists
Selenomethionine Se 75
Sethotope, Selenomethionine (75Se), Selenomethionine (75 Se)
T346081187-56-0
Selenomethionine Se 75, as a Radioactive Agent, can be used as a Diagnostic Aid for Pancreas Function Determination.
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Temozolomide
TZM, TMZ, NSC 362856, CCRG 81045
T117885622-93-1
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
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TargetMol | Inhibitor Hot
Linsitinib
OSI-906
T6017867160-71-2
OSI-906 (Linsitinib (OSI-906)) is an orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. Linsitinib selectively inhibits IGF-1R, which may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. Overexpressed in a variety of human cancers, IGF-1R stimulates cell proliferation, enables oncogenic transformation, and suppresses apoptosis.
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TargetMol | Inhibitor Hot
Nirmatrelvir
T93512628280-40-8
PF-07321332 is a potent and orally active inhibitor of SARS-CoV 3C-like protease (3CLPRO) .
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TargetMol | Inhibitor Hot
Fluorobexarotene
T113031190848-23-7In house
Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene. Fluorobexarotene  is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
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6-8 weeks
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OMDM-6
T12307616884-67-4In house
OMDM-6 is a dual agonist of TRPV1(EC50 = 75 nM) and CB1 (Ki = 3.2 μM). OMDM-6 inhibits anandamide cellular uptake with a Ki of 7.0 μM.
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6-8 weeks
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Atagabalin HCl
PD-0200390 HCl, Atagabalin HCl(223445-75-8 Free base)
T30188L223445-67-8In house
Atagabalin HCl is a novel voltage-dependent calcium channel (VDCC) α2δ subunit (1 and 2) ligand that affects slow-wave sleep and can be used to treat insomnia.
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(Iso)-Atagabalin HCl
(Iso)-Atagabalin HCl((Iso)-223445-75-8)
T30188L1223445-68-9In house
(Iso)-Atagabalin HCl(isomer-Atagabalin HCl) is an alpha -2- delta ligand that can be used to treat non-restorative sleep.
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IRAK4-IN-10
T619312681278-09-9In house
IRAK4-IN-10 (compound 75) is a potent IRAK4 inhibitor (IC50 = 1.5 nM) that can block the MyD88-dependent signaling pathway and has research potential in inflammatory diseases, autoimmune diseases, and cancer.
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7-10 days
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Nicorandil
SG-75
T007565141-46-0
Nicorandil (SG-75)(Ikorel) acts by relaxing the smooth muscle of the blood vessels, especially those of the venous system. It undertakes this through two methods. Firstly, by activating potassium channels, and secondly by donating nitric oxide to activate the enzyme guanylate cyclase. Guanylate cyclase causes activation of cGMP leading to both arterial and venous vasodilatation by de-phosphorylation of the myosin light chain.
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Isoliquiritigenin
Isoliquiritigen, ISL, GU17
T0725961-29-5
Isoliquiritigenin (ISL) is a flavonoid natural product that inhibits influenza virus replication (EC50=24.7 μM) and aldose reductase activity (IC50=320 nM). Isoliquiritigenin has antitumor activity.
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Trimetazidine dihydrochloride
Yoshimilon, Kyurinett, Vastarel F
T098813171-25-0
Trimetazidine dihydrochloride (Vastarel F) can improve myocardial glucose utilization by inhibiting fatty acid metabolism. Trimetazidine is the first cytoprotective anti-ischemic agent, also used as a vasodilator in ischemic heart disease or angina.
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L-Pipecolic acid
L-Homoproline, H-HoPro-OH
T47623105-95-1
L-Pipecolic acid (L-Homoproline) is a breakdown product of lysine, accumulates in body fluids of infants with generalized genetic peroxisomal disorders, such as Zellweger syndrome, neonatal adrenoleukodystrophy.
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2-(Naphthalen-1-yl)acetonitrile
T65716132-75-2
2-(Naphthalen-1-yl)acetonitrile is a useful organic compound for research related to life sciences. The catalog number is T65716 and the CAS number is 132-75-2.
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7-10 days
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DSRM-3716
T886058142-99-7
Isoquinoline, 5-iodo- is a potent and selective inhibitor of SARM1(IC50 = 75 nM) by preventing axonal degeneration and by allowing functional recovery of a metastable pool of damaged, but viable, axons.
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METHYL UNDECANOATE
T95051731-86-8
Methyl undecanoate is a natural product found in Daphne odora.
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Methyl tridecanoate
TN69191731-88-0
Methyl tridecanoate is a natural product.
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Hyocholic acid
HCA
TN7024547-75-1
Hyocholic acid is a natural product for research related to life sciences. The catalog number is TN7024 and the CAS number is 547-75-1.
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Cpd.7 of 1326852-06-5
T95592411843-75-7In house
Cpd.7 of 1326852-06-5 is a useful organic compound for research related to life sciences. The catalog number is T9559 and the CAS number is 2411843-75-7.
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    Clozapine
    LX 100-129, HF 1854
    T04555786-21-0
    Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A 2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.
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    C75
    C-75
    T10657218137-86-1
    C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).C75 increases CPT1 activity and reduces DIO.
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    6-8 weeks
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    β-Elemene
    Levo-β-elemene, (-)-β-Elemene
    T13476515-13-9
    β-Elemene (Levo-β-elemene) is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.
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    Dactolisib Tosylate
    BEZ235 Tosylate, NVP-BEZ 235 Tosylate
    T145521028385-32-1
    Dactolisib Tosylate (BEZ235 Tosylate) is a dual kinase inhibitor targeting PI3K and mTOR, with IC50 values of 4, 75, 7, and 5 nM for PI3Kα, β, γ, and δ, respectively. It also inhibits mTORC1 and mTORC2.
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    6-8 weeks
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    IDO-IN-7
    GDC-0919, NLG919, Navoximod, NLG-919 analogue
    T18061402836-58-1
    IDO-IN-7 (NLG-919 analogue) is a potent inhibitor of the IDO (indoleamine-(2, 3)-dioxygenase) pathway.
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