60398-91-6

Bufuralol hydrochloride belongs to the class of beta-adrenoreceptor antagonists and is a potent, orally active, non-selective beta-adrenoreceptor antagonist with partial agonist activity. Bufuralol hydrochloride is a prototypical CYP2D6 probe substrate (Km = 5-50 microM) and is extensively used in biochemical studies to characterize CYP2D6 enzymatic activity and evaluate genetic variants.

Bufuralol (Ro 3-4787) is an orally active β-adrenergic receptor blocker with a certain degree of sympathomimetic effects and can be used to study cardiovascular diseases.