54527-84-3

Nicardipine hydrochloride (YC-93 Hydrochloride) is the hydrochloride salt form of nicardipine, a synthetic derivative of nitrophenyl-pyridine and potent calcium channel blocker, Nicardipine (Nifedipine Family) blocks calcium ions from certain cell walls and inhibits contraction of coronary and peripheral arteries, resulting in lowered oxygen requirements for heart muscle and decreased arterial contraction and spasm. It is used clinically as a cerebral and coronary vasodilator.

(S)-(+)-Nicardipine-D3 is a deuterated compound of  (S)- (+)- Nicardipine (T12221). (S)- (+)- Nicardipine has a CAS number of 1432061-50-1.

(S)-Nicardipine is the less active S enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).

Nicardipine-D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride (T1215).

(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).

Nicardipine (Cardene), a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.

(R)-(-)-Nicardipine-D3 is a deuterated compound of  (R)- (-)-Nicardipine (T12221). (R)- (-)-Nicardipine has a CAS number of 1432061-50-1.