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Pyridoxal phosphate (Vitamin B6 phosphate) is the active form of vitamin B6 and a coenzyme for many pyridoxal phosphate (PLP)-dependent enzymes. PLP is involved in numerous enzymatic transamination, decarboxylation and deamination reactions; it is necessary for the synthesis of amino acids and amino acid metabolites, and for the synthesis and/or catabolism of certain neurotransmitters, including the conversion of glutamate into gamma-aminobutyric acid (GABA) and levodopa into dopamine. PLP can be used as a dietary supplement in cases of vitamin B6 deficiency. Reduced levels of PLP in the brain can cause neurological dysfunction.

Pyridoxal phosphate (Standard) is the analytical standard of Pyridoxal phosphate, primarily used for research and analytical applications. Pyridoxal phosphate (PLP) is the active form of Vitamin B6 and acts as an essential cofactor for over 140 enzymatic reactions, including transamination, decarboxylation, and racemization. Additionally, it has been shown to inhibit the activity of reverse transcriptases and is utilized in studies concerning tardive dyskinesia.