5'-guanosine

Guanosine-5'-triphosphate disodium salt (5'-GTP disodium salt) is an enhancer of myogenic cell differentiation and serves as an energy source for translation and other critical cellular processes.

5'-GTP trisodium salt hydrate, an activator of the signal-transducing G proteins, serves as a precursor of mononucleotide units in the enzymatic biosynthesis of DNA and RNA.

Guanosine 5'-O-(2-thiodiphosphate) (trisodium) (GDPβS (trisodium)) is a non-hydrolyzable derivative of GDP. It acts as an inhibitor of adenylate cyclase (AC) with a Ki value of 600 nM. In the absence of glutamic-pyruvic transaminase (GPT) in cortical membranes of rodent models, it can partially activate AC, with an EC50 of 400 nM. Furthermore, Guanosine 5'-O-(2-thiodiphosphate) (trisodium) prevents the norepinephrine-induced release of nitric oxide from ventricular myocytes.

Guanosine 5'-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5'-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR2B) linked to the inward-rectifier potassium channel 6.1 (Kir6.1) in HEK293T cells in a patch-clamp assay.3 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Biochemistry(2002) 2.Vetter, I.R., and Wittinghofer, A.The guanine nucleotide-binding switch in three dimensionsScience294(5545)1299-1304(2001) 3.Yamada, M., Isomoto, S., Matsumoto, S., et al.Sulphonylurea receptor 2B and Kir6.1 form a sulphonylurea-sensitive but ATP-insensitive K+ channelJ. Physiol.499(Pt 3)715-720(1997)

Guanosine 5'-triphosphate-5'-adenosine, known as a 5′ cap analog, serves as a fluorescent substrate analog.

N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog employed in the process of in vitro RNA transcription.

5'-O-DMT-2'-O-iBu-N-Bz-Guanosine can be used for the silyl protection of ribonucleosides.

2′,3′,5′-Tri-O-acetyl Guanosine is a useful organic compound for research related to life sciences. The catalog number is T67464 and the CAS number is 6979-94-8.

Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel, serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin interaction, and modulating the interleukin-6 (IL-6)/stat-3 pathway. It is utilized in research on inflammation-related conditions, including anemia of inflammation (AI).

N7-Methylguanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium, a dinucleotide cap analog, facilitates in vitro RNA transcription [1].

2'-O-(2-Methoxyethyl)guanosine 5'-triphosphate (ammonium), a purine nucleoside analog, exhibits significant antitumor properties, especially against indolent lymphoid malignancies, by inhibiting DNA synthesis and inducing apoptosis, among other mechanisms [1].

Sp-Guanosine-5'-O-(1-thiotriphosphate) (Sp-GTP-α-S), an isomer of the sulfur-containing nucleotide derivative GTP-α-S, demonstrates the ability to bind tubulin and facilitate microtubule assembly in cell-free assays at a concentration of 20 mM.

Guanosine 5'-diphosphate ditromethamine (GDP ditromethamine) is a nucleoside diphosphate that activates ATP-sensitive K+ channels. It acts as a potential iron mobilizer, inhibiting the interaction between hepcidin and ferroportin, and modulating the IL-6/STAT-3 pathway. This compound finds application in inflammation research, such as studying anemia of inflammation (AI).

Guanosine 5'-diphosphate-13C10 (GDP-13C10) dilithium is a 13C-labeled version of Guanosine 5'-diphosphate. GDP is a nucleoside diphosphate that activates adenosine 5'-triphosphate-sensitive K+ channels. It also functions as a potential iron mobilizing agent, capable of disrupting the hepcidin-ferroportin interaction and modulating the IL-6/STAT-3 pathway. Guanosine 5'-diphosphate is utilized in research related to inflammatory conditions, such as anemia of inflammation (AI).

2'-O-(2-Methoxyethyl)guanosine  5'-triphosphate ammonium salt is a useful organic compound for research related to life sciences and the catalog number is TNU1082.

N2-iso-Butyroyl-2'-deoxy-5'-O-(4,4'-dimethoxytrityl)-guanosine-3'-(4-nitrophenoxyl)butanedioate is a useful organic compound for research related to life sciences and the catalog number is TNU1187.

3',5'-TIPS-N-PAc-Guanosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH open.

N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-3'-O-Methyl guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

N2-iso-Butyroyl-5'-O-DMT-3'-O-(methoxyethyl)guanosine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w/NH2/OH open.

N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine is an essential organic compound for life sciences research (Catalog No. TNU1656, CAS No. 2382942-31-4).

N2-iBu-5'-O-DMTr-2'-O-hexadecanyl guanosine 3'-CED phosphoramidite (catalog number: TNU1657, CAS number: 2382942-32-5) is a valuable organic compound for life sciences research.

5'-DMT-3'-CE-2'-TBDMS 2-cyanoethoxycarbonyl, 2-(4-nitrophenyl)ethyl-guanosine is a nucleotide analog employed in nucleic acid synthesis.

GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms.

Guanosine-13C10,15N5 is a version of Guanosine labeled with isotopes 13C and 15N. Guanosine (DL-Guanosine) is a type of nucleoside, consisting of guanine attached to a ribose ring through a β-N9-glycosidic bond. It has activity against HSV.