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49671-76-3

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  • ZLN005-D4
    TMID-04592410443-42-2
    ZLN005-D4 is the deuterated form of ZLN005. ZLN005 (T1802) acts as a novel activator of the peroxisome proliferator-activated receptor coactivator (PGC-1α).
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  • ZLN005 hydrochloride
    T2117972319647-97-5
    ZLN005 (hydrochloride) is an activator of the peroxisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC-1α). It enhances the expression of PGC-1α and downstream genes in skeletal muscle cells, leading to improved glucose utilization and fatty acid oxidation. In diabetic db/db mice, ZLN005 (hydrochloride) elevates the transcription of PGC-1α and downstream genes in skeletal muscle, boosts fat oxidation, and enhances glucose tolerance, pyruvate tolerance, and insulin sensitivity.
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    10-14 weeks
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