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3a-hydroxy-5b-cholanic acid

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Lithocholic acid
3α-Hydroxy-5β-cholanic acid
T2202434-13-9
Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM), EphA2 antagonists (IC50=48, 66 μM) and EphB4 antagonists (IC50=141 μM). Lithocholic acid can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is a cleanser that dissolves fat for absorption and is itself absorbed.
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7-Ketolithocholic acid
3α-Hydroxy-7-oxo-5β-cholanic acid
T135224651-67-6
7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid) is capable of absorption and suppresses the production of endogenous bile acid and the secretion of biliary cholesterol.
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