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Results for "

3-deazauridine

" in TargetMol Product Catalog
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3-Deazauridine
NSC 126849
T3686623205-42-7
3-Deazauridine (NSC-126849) is a structural analog of uridine that inhibits the biosynthesis of Cytidine-5'-Triphosphate by competitive inhibition of Cytidine Triphosphate synthetase which is considered to be the primary mode of action of this nucleoside analog.
  • $48
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3'-Deoxy-3-deazauridine
TNU02512095417-74-4
Nucleoside Derivatives - 3'-Deoxy nucleosides, 3-Deazauridines, Pyridine nucleosides
  • Inquiry Price
7-10 days
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5'(R)-C-Methyl-3-deazauridine
TNU02602305415-82-9
Nucleoside Derivatives - 5'-Modified nucleosides; 3-Deazauridines
  • Inquiry Price
7-10 days
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3'-beta-C-Ethynyl-3-deazauridine
TNU0534
3'-beta-C-Ethynyl-3-deazauridine is a Nucleoside Derivative - 3'-Modified nucleoside, 3-Deazauridine.
  • Inquiry Price
7-10 days
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2',3',5'-Tri-O-benzoyl-3-deazauridine
TNU081923220-74-8
Nucleosides and Reagents - 3-Dezauridine; Pyridine nucleoside
  • Inquiry Price
7-10 days
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3'-Deoxy-3'-flluoro-3-deazauridine
TNU08312072145-34-5
Nucleosides and Reagents - Fluoro-modified nucleoside; 3-Deazauridine; Pyridine nucleoside
  • Inquiry Price
7-10 days
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3'-Azido-3'-deoxy-3-deazauridine
TNU09232305416-04-8
Nucleoside Derivatives –Azido-nucleosides, 3-Deaza uridines, 3'-Modified nucleosides; Pyridine nucleosides
  • Inquiry Price
7-10 days
Size
QTY
3'-beta-C-Methyl-3-deazauridine
TNU1492
3'-beta-C-Methyl-3-deazauridine is a Nucleoside Derivative - 3'-Modified nucleoside, 3-Deazauridine.
  • Inquiry Price
7-10 days
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QTY
Sorafenib
Bay 43-9006
T0093L284461-73-0
Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.
  • $34
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Gemcitabine
NSC 613327, LY188011
T025195058-81-4
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
  • $34
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TargetMol | Inhibitor Hot
Cyclosporin A
Cyclosporine A, Cyclosporine, Ciclosporin
T094559865-13-3
Cyclosporin A is a natural product and an active fungal metabolite, classified as a cyclic polypeptide immunosuppressant. It binds to cyclophilin and inhibits the activity of calcineurin (IC₅₀ = 7 nM) as well as CD11a/CD18 adhesion molecules. It is commonly used to induce uremia models.
  • $36
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5-Fluorouracil
NSC 19893, Fluorouracil, 5-FU, 5-Fluoracil
T098451-21-8
5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.
  • $30
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IBMX
Methylisobutylxanthine, Isobutylmethylxanthine, 3-Isobutyl-1-methylxanthine, 1-Methyl-3-Isobutylxanthine
T171328822-58-4
IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 μM). IBMX enhances the intracellular cAMP level.
  • $33
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TargetMol | Inhibitor Hot
Erastin
T1765571203-78-6
Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations.
  • $41
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TargetMol | Inhibitor Hot
LY294002
SF 1101, NSC 697286, LY 294002
T2008154447-36-6
LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5/0.57/0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 activates apoptosis and autophagy.
  • $34
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TargetMol | Inhibitor Hot
Quercetin
Sophoretin
T2174117-39-5
Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.
  • $42
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TargetMol | Inhibitor Hot
(-)-Epigallocatechin Gallate
Epigallocatechol Gallate, EGCG
T2988989-51-5
(-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.
  • $43
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Staurosporine
CGP 41251, Antibiotic AM-2282, AM-2282
T668062996-74-1
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
  • $56
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TargetMol | Inhibitor Hot
BI-2493
T720612937344-16-4In house
BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.
  • $629
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TargetMol | Inhibitor Hot
Q-VD-OPH
Quinoline-Val-Asp-Difluorophenoxymethylketone
T02821135695-98-5
Q-VD-OPh is an irreversible caspase inhibitor with an IC50 value of 48 nM against caspase-7 and between 25 and 400 nM against caspase-1, 3, 8, 9, 10, 12. Q-VD-OPh inhibits HIV infection and can cross the blood-brain barrier.
  • $47
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TargetMol | Inhibitor Hot
Lenvatinib
E7080
T0520417716-92-8
Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity. Lenvatinib has the strongest inhibitory activity on VEGFR2 and VEGFR3 (IC50=4/5.2 nM). Lenvatinib has strong anti-tumor activity.
  • $40
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TargetMol | Inhibitor Hot
Rutin
Rutoside, Quercetin 3-O-rutinoside
T0795153-18-4
Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
  • $36
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TargetMol | Inhibitor Hot
Corticosterone
Kendall's compound B, Corticosterone (From plants), 17-Deoxycortisol, 11β,21-Dihydroxyprogesterone
T0948L50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.
  • $30
In Stock
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TargetMol | Inhibitor Hot
LDL-IN-3
T10063180908-67-2In house
LDL-IN-3 shows anti-atherosclerotic and antioxidant activities.
  • $388
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TargetMol | Inhibitor Hot