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(3)
By Target- CXCR
- HIV Protease(2)
- Akt(1)
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Results for "
12g5 mab-cxcr4
" in TargetMol Product Catalog- Inhibitors & Agonists3
AMD 3465 hexahydrobromide
GENZ-644494 (hexahydrobromide)
T7208185991-07-5
AMD 3465 hexahydrobromide (GENZ-644494 (hexahydrobromide)) is a CXCR4 receptor antagonist with potential anticancer and anti-HIV activity.
- $31
Size
QTY
AMD 3465
GENZ-644494
T14208185991-24-6
AMD 3465 also potently inhibits the replication of X4 HIV strains (IC50: 1-10 nM). However, it has no effect on CCR5-using (R5) viruses. AMD 3465 (GENZ-644494) is a potent antagonist of CXCR4, inhibits binding of 12G5 mAb and CXCL12AF647 to CXCR4, with IC
- $1,520
Size
QTY
Hit 14
T88707440338-68-1
Hit 14, a CXCR4 (C-X-C chemokine receptor type 4) inhibitor, demonstrates an IC50 of 254 nM. It inhibits migration and invasion of MDA-MB-231 cells and suppresses Akt phosphorylation, exhibiting anti-inflammatory activity. Furthermore, Hit 14 improves ear swelling and damage in a mouse model.
- $1,520
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QTY
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