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Urocanic acid (4-Imidazoleacrylic acid), synthesized in the epidermis, functions as a primary absorber of ultraviolet (UV) radiation in mammalian skin.

Urocanic acid-13C3 is the 13C-labeled form of Urocanic acid. In the skin, Urocanic acid (T4759) primarily acts as a photoreceptor and naturally exists in the trans-urocanic acid form.

cis-Urocanic acid-13C3 is a 13C-labeled version of cis-Urocanic acid. This compound acts as an agonist for the 5-HT2A receptor. It binds to 5-HT receptors with high affinity, demonstrating a Kd of 4.6 nM. Additionally, cis-Urocanic acid (T10824) serves as an immunomodulator, inducing immunosuppression through its interaction with the 5-HT2A receptor.

cis-Urocanic acid ((E)-Urocanic acid) is a 5-HT2A receptor agonist (Kd: 4.6 nM). It is an immune modulator that induces immunosuppression by binding to the 5-HT2A receptor.

trans-Urocanic Acid ((E)-Urocanic acid), a compound predominantly distributed in the hippocampus and prefrontal cortex, is an isomer of cis-UCA, an epidermal UV-protectant, which enhances the stability of tenofovir eplerenomide in long-acting HIV applications. trans-Urocanic acid potently modulates immune trans-urocanic acid effectively modulates immune function, inhibits human natural killer cell activity in vitro, and can be used in Alzheimer's disease research.

Urocanic Acid-13C3 (Standard) is a reference standard of Urocanic Acid-13C3 intended for quantitative analysis, quality control, and related biochemical research applications. Urocanic acid-13C3 is the 13C-labeled form of Urocanic acid. In the skin, Urocanic acid primarily acts as a photoreceptor and naturally exists in the trans-urocanic acid form.