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(1)
By Target- BTK
- EGFR(1)
- HER(1)
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By Target By ResearchField- Cancer(1)
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Results for "
(s) sunvozertinib
" in TargetMol Product Catalog.- Inhibitors & Agonists1
- (S)-SunvozertinibN-[5-[[4-[5-Chloro-4-fluoro-2-(2-hydroxypropan-2-yl)anilino]pyrimidin-2-yl]amino]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]-4-methoxyphenyl]prop-2-enamide, DZD9008T93042370013-49-1(S)-Sunvozertinib (DZD9008) is a rationally designed selective, irreversible EGFR/HER2 inhibitor.
- $54
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- Sunvozertinib
DZD-9008, DZD9008, DZD 9008T641242370013-12-8Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor, with inhibitory effects on EGFR, Her2, and mutant epidermal growth factor. Sunvozertinib (DZD9008) showed inhibitory effects on EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutations, as well as Her2 exon 20 YVMA and EGFR WT A431 with IC50 of 20.4, 20.4, 1.1, 7.5, and 80.4 nM.- $30
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