Lycopodiopsida

1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.

(-)-Huperzine A (HupA) , an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibitor and has been widely used in China for the treatment of Alzheimer's disease (AD).

2,3-Dihydrohinokiflavone is a suppressor of matrix metalloproteinases (MMP) gene expression and shows strong activity against Leishmania with an IC50 of 1.6 μM.

Heveaflavone inhibits Topoisomerase I and scavenges DPPH free radical with anti-proliferation and antioxidant effects.

Tetrahydroamentoflavone is a potent XO inhibitor (IC50 = 92 nM, Ki = 982 nM) with anti-inflammatory effects. Tetrahydroamentoflavone can be used for studies about inflammation and gout.

Lycoclavanol exhibits acetylcholinesterase inhibition activity.

Sotetsuflavone, with an IC50 of 0.16 μM, stands as the most active compound in its series, acting as a potent inhibitor of DENV-NS5 RdRp (Dengue virus NS5 RNA-dependent RNA polymerase).

21-Episerratenediol may be as a potent cancer chemopreventive agent.

26-Nor-8-oxo-alpha-onocerin can promote the osteoblast proliferation rate, the effect is time-dependent,concentration-dependent and differentiation state-dependent.

alpha-Onocerol is a natural product for research related to life sciences. The catalog number is TN3389 and the CAS number is 511-01-3.

Lycernuic acid A is a natural product of Lycopodium, Lycopodiaceae. The catalog number is TN4466 and the CAS number is 53755-77-4. Lycernuic acid A can be used as a reference standard.

21-Episerratriol is a natural product of Lycopodium, Lycopodiaceae. The catalog number is TN2808 and the CAS number is 24513-57-3. 21-Episerratriol can be used as a reference standard.

N-Demethyl-alpha-obscurine is a natural product from Lycopodium japonicum.

Serratenediol demonstrates strong inhibitory effects on the Epstein-Barr virus early antigen (EBV-EA) activation without showing any cytotoxicity, its effects being stronger than that of a representative control, oleanolic acid. Serratenediol can promote

6alpha-Hydroxylycopodine is a natural product from Phlegmariurus fargesii.

Selaginellin F is a natural product from Selaginella pulvinata.

Methyl lycernuate A is a natural product for research related to life sciences. The catalog number is TN4550 and the CAS number is 56218-46-3.

Lucidioline is a natural product from Lycopodium japonicum.

Selaginellin has a neuroprotective effect against L-glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis via scavenging reactive oxygen species and up-regulating the expression of klotho gene. Selaginellin shows

Ikshusterol is a natural product for research related to life sciences. The catalog number is TN4248 and the CAS number is 34427-61-7.

Serratriol is a natural product for research related to life sciences. The catalog number is TN5000 and the CAS number is 13956-52-0.

Phlegmanol C is a natural product for research related to life sciences. The catalog number is TN4763 and the CAS number is 1260-05-5.

Alpha-Onocerin diacetate is a natural product of Lycopodium, Lycopodiaceae. The catalog number is TN3388 and the CAS number is 34434-99-6. Alpha-Onocerin diacetate can be used as a reference standard.

Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.