Digitoxin (Digitoxinum) is an effective Na+/K+-ATPase inhibitor (EC50 value: 0.78 μM).

Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias associated with reentry mechanisms. It inhibits the Na-K-ATPase membrane pump, increasing intracellular sodium and calcium concentrations.

Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells.

Digoxigenin bisdigitoxoside (Bisdigoxigenin) is a digoxigenin metabolite with anticancer activity and cytotoxicity.

Gitoxin is a natural Na⁺/K⁺-ATPase inhibitor and metabolite of digitoxin, exhibiting antiarrhythmic activity with μM-level inhibition of human erythrocyte isoenzymes.