Noroxyhydrastinine exhibits potent melanogenesis-inhibitory activities, it inhibits melanogenesis, at least in part, by inhibiting the expression of protein levels of tyrosinase, TRP-1, and TRP-2 in α-MSH-stimulated B16 melanoma cells.

Thalrugosaminine shows promising antibacterial activity with MIC values of 64-128ug ml and Staphylococcus species is the most sensitive strains. Thalrugosaminine possesses hypotensive activity in rabbits and is active against Mycobacterium smegmatis.

Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.

Thalrugosidine is a natural product from Thalictrum foliolosum DC.

Thalifendine is one of the main products of Berberine demethylation catalyzed by CYP51 (secreted by intestinal flora), which has anti-inflammatory effects, reduces intestinal inflammation, improves intestinal barrier function, and reduces the production of inflammatory factors.

Thalidezine, a novel AMPK activator, eliminates apoptosis-resistant cancer cells through energy-mediated autophagic cell death, it can inhibit the growth of mouse L1210 cells in vitro. Thalidezine possesses antimicrobial activity against Mycobacterium sme

Thalirugidine is a natural product from Thalictrum foliolosum DC.