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Appendicula
Coelonin
TN368882344-82-9
Coelonin is a dihydrophenanthrene compound with anti-inflammatory activity. Coelonin can inhibit the phosphorylation of PTEN induced by LPS, and inhibit the activation of NF-κB and the degradation of p27^Kip1 by negatively regulating PI3K/AKT signaling pathway. Coelonin can also inhibit the phosphorylation and degradation of IκBα, thus up-regulating the level of IκBα protein.
- $1,530
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