Pennogenin 3-O-beta-chacotrioside, isolated from *Paris polyphylla*, exhibits anti-colorectal cancer activity by modulating autophagy through increased expression of autophagy-related proteins LC3 and Beclin-1.

Polyphyllin D induces apoptosis via the mitochondrial apoptotic pathway as evidenced by decreased Bcl-2 expression levels, disruption of MMP and increased Bax, cytochrome C, and cleaved-caspase-3 levels. Polyphyllin D has an anti-angiogenic effect. Polyphyllin D has toxicity in human RBCs as well as its underlying mechanism for the hemolysis and eryptosis/erythroptosis. Polyphyllin D has strong anticancer activity, can overcome drug resistance in R-HepG2 cells and elicit programmed cell death via mitochondrial dysfunction.

1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.

Formosanin C (Polyphyllin B) is a compound isolated from Rhizoma Paridis, showed pro-apoptosis and immunoregulation with antitumor activity in cultured cells and animal systems.

Polyphyllin G (Polyphyllin VII), the the main member of polyphyllin family, shows strong anticancer activity against several carcinomas, including lung cancer, breast cancer, colorectal cancer, cervical cancer, hepatocellular carcinoma and osteosarcoma.

Zingiberen newsaponin is a steroidal saponin from Dioscorea zingiberensis.

Polyphyllin II (Chonglou Saponin II) has hemostasis, expectorant, bacteriostasis, anticytotoxic, anti-pregnancy kill sperm effects.

Polyphyllin H can be extracted from loblolly pine and rhizomes, has antitumor activity, and is used in studies of inflammation, fractures, and convulsions.

Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis. It exhibits pro-inflammatory properties, stimulating nitric oxide production, inducing gene expression, and promoting the production of TLRs, cytokines, chemokines, and cellular adhesion molecules.

Pennogenin steroidal saponins could be utilized to develop anticancer medicines.

Polyphyllin F is a natural product of Paris, Liliaceae. The catalog number is TN4815 and the CAS number is 76296-74-7. Polyphyllin F can be used as a reference standard.

Polyphyllin C is a natural product

Dichotomin is a natural product of Paris, Liliaceae. The catalog number is TMA2055 and the CAS number is 53093-47-3. Dichotomin can be used as a reference standard.

Parisyunnanoside B is a natural product of Paris, Liliaceae. The catalog number is TMA2053 and the CAS number is 945865-37-2. Parisyunnanoside B can be used as a reference standard.