Skullcapflavone II is a flavonoid derived from Scutellaria baicalensis, a widely used herbal medicine in anti-inflammatory and anticancer therapy. Skullcapflavone II may have therapeutic potential for the treatment of allergic asthma.Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts potent antimicrobial activity against M. aurum and M. bovis BCG

Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.

Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.

Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.

Oroxylin A 7-O-β-d-glucuronide and wogonoside should also be served as the chemical markers together with baicalin for the quality control of herbs and proprietary traditional Chinese medicine (PTCM) products of radix Scutellariae. Oroxylin A 7-O-glucuronide, Oroxin A, and Oroxin B can bind to the stem region of α-hemolysin (α-HL), when inhibiting the hemolytic activity of α-HL. Oroxylin A 7-O-glucuronide and 4', 5, 7-trihydroxy-6-methoxyflavone at a concentration of 100 microM inhibit 34 and 43% of total prolyl oligopeptidase (POP) activity, respectively.

5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.

Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.

1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces neurite outgrowth in PC12 cells. 3. Negletein shows a comparable redox-active potential, and it (50 μM, 4 h) can activate Nrf2. 4. Negletein shows significant antimicrobial activity. 5. Negletein has anti-hypoxia activity, it can significantly prolong the survival time of hypoxic mice.6. Negletein has anti- Alzheimer's disease activity, it inhibits the iron-dependent formation of ROS and also blocks the iron-induced oligomerization of amyloid beta 42 in vitro. 7. Negletein (IC50: 3.89 + - 0.39 microM) exhibits potent inhibitory activity against nuclear factor of activated T cells (NFAT) transcription factor.

Chrysin 6-C-glucoside 8-C-arabinoside and Chrysin-6-C-arabinosyl-8-C-glucoside are α±-glucosidase inhibitors widely used in the treatment of type 2 diabetes.

Scutellarein tetramethyl ether (4',5,6,7-Tetramethoxyflavone) is extracted from Siam weeds and demonstrates anti-inflammatory activity via the NF-κB pathway.

2',3,5,6',7-Pentahydroxyflavanone (3,5,7,2',6'-Pentahydroxyflavanone) is a natural product isolated from the roots of *Scutellaria baicalensis*.

5,7-Diacetoxy-8-methoxyflavone, derived from the roots of Scutellaria baicalensis, inhibits cAMP phosphodiesterase.

Baicalin methyl ester shows inhibitory effects on the Avian Myeloblastosis Virus reverse transcriptase (AMV-RT).

Chrysin 6-C-arabinoside 8-C-glucoside and chrysin-6-C-glucosyl-8-C-arabinoside are α±-glucosidase inhibitors, which are widely used in the treatment of type 2 diabetes.

Rivularin (Skullcapflavone) is a flavonoid compound derived from Radix scutellariae. Rivularin can be used as a reference standard.

4'-Hydroxywogonin (8-Methoxyapigenin), a natural flavonoid with anti-inflammatory properties, reduced the production of pro-inflammatory cytokines (e.g., TNF-α, IL-6, and IL-1β), inhibited the TAK1/IKK/NF-κB signaling pathway, and reduced the phosphorylation of MAPKs and the PI3/Akt signaling pathway.

Terpinyl Butyrate is a terpenoid ester widely used in biochemical experiments and drug synthesis research.

Apigenin 5-O-beta-D-glucopyranoside has inhibitory activity against the enzyme yeast a-glucosidase, withthe IC50 value of 287.12 muM.

Viscidulin III tetraacetate is a natural product for research related to life sciences. The catalog number is TN5239 and the CAS number is 96684-81-0.

2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one is a natural product of Scutellaria, Lamiaceae. The catalog number is TN2722 and the CAS number is 1167483-18-2. 2-(4-Hydroxyphenyl)-6-methyl-2,3-dihydro-4H-pyran-4-one can be used as a reference standard.

6-O-Nicotinoylscutebarbatine G shows cytotoxic activities against three human tumor cell lines, namely, HONE-1 nasopharyngeal, KB oral epidermoid carcinoma, and HT29 colorectal carcinoma cells, and with IC50 values in the range of 2.1 5.7 μM.

Scutellaric acid is a natural product of Scutellaria, Lamiaceae. The catalog number is TN4979 and the CAS number is 102919-76-6. Scutellaric acid can be used as a reference standard.

Scutebarbatine Z is a natural product from Scutellaria barbata.

Viscidulin II can be potential therapeutic agents against P. acnes-induced skin inflammation, it can significantly suppress P. acnes-induced IL-8 and IL-1β production in THP-1 cells, concomitant intradermal injection of viscidulin II with P. acnes can effectively attenuate P. acnes-induced ear swelling, and decrease the production of IL-6 and tumor necrosis factor-α in ear homogenates.