1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a significant analgesic effect in rodent behavioral models of inflammatory and neuropathic pain, the m

Gelsevirine, a novel STING-specific inhibitor, is an alkaloid from Gelsemium elegans with anxiolytic and antiproliferative activities that inhibits interferon and inflammatory cytokine induction in macrophages exposed to STING agonists, and attenuates STING-related inflammation in sepsis.

Humantenine, a naturally occurring indole alkaloid derived from *Gelsemium elegans*, HCT116 cell injury induced by humantenine was associated with the abnormal mRNA expression of m6A regulators

Sempervirine nitrate is an alkaloid extracted from Gelsemium elegans Benth., inhibiting HCC tumor growth and enhancing sorafenib's antitumor effects in vivo. It inhibits HCC proliferation and induces apoptosis by modulating the Wnt β-catenin pathway.

11-Hydroxyhumantenine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN6035 and the CAS number is 122590-04-9. 11-Hydroxyhumantenine can be used as a reference standard.

11-Hydroxygelsenicine is a natural product of Gelsemium, Loganiaceae. The catalog number is TN6031 and the CAS number is 1195760-68-9. 11-Hydroxygelsenicine can be used as a reference standard.