Lupanine ((+)-Lupanine), a naturally occurring quinolizidine alkaloid, potently affinity and activates nicotinic acetylcholine receptor (nAChR) (Ki=500 nM), and shows significant neuroprotection against soluble amyloid β-oligomers (SO-Aβ) toxicity in cellular models in association with the anti-apoptotic PI3K/ Akt/Bcl-2 signaling pathway with anti-Alzheimer's disease potential. Improves glucose homeostasis by affecting KATP channels and enhancing insulin secretion with therapeutic potential for type 2 diabetes.
Coenzyme Q10 (Standard) is a certified reference standard of Coenzyme Q10 designed for use in quantitative analysis, analytical method validation, quality control procedures, and biochemical experimentation. Coenzyme Q10 (CoQ10), is a naturally derived molecule produced by Fujikura-type fungi that functions as a critical electron carrier within the mitochondrial respiratory chain, thereby playing an essential role in cellular energy metabolism and redox balance in biological systems.
Anagyrine, is the responsible teratogen from teratogenic lupins, can produce congenital deformities in calves typical of crooked calf disease; it also can induce red cell aplasia, vascular anomaly, and skeletal dysplasia.(-)-Anagyrine and (-)--Methylcytisine have nematicidal activities against Pine Wood Nematodes.