Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression [3].

Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.

Diphenylheptane A (DHPA), isolated from the rhizomes of the plant Curcuma longa L., is a phenolic dialog compound with antimicrobial activity.

1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).

Curdione ((+)-Curdione) inhibits CYP3A4 activity and the production of prostaglandin E2. Curdione inhibits proliferation of MCF-7 cells by inducing apoptosis. Curdione may be a candidate for anti-inflammatory and Y chemopreventive agents.

Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 production from purified basophils.

Zederone is a natural sesquiterpene that modulates inflammatory response, smooth muscle relaxation and endocrinology to treat dysmenorrhea; down-regulates mRNA levels of mTOR and p70s6K to inhibit the proliferation of ovarian cancer cells, and interacts with hypoglycemic proteins 3L4Y and 5UBA to be anti-diabetic and anti-oxidant.

1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .

Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) demonstrates selective cytotoxic activities against nine tested cancer cell lines.

β-Ocimene, a volatile substance released in large quantities from the leaves and flowers of many plant species, is a multifaceted attractant for a wide range of pollinators, possesses antileishmanial protozoan activity, and inhibits the growth of M. persicae.

Furanodiene is a type of terpenoid natural product that can inhibit the function of efflux transporter Pgp and reduce the level of Pgp protein. It exerts anti-cancer effects through anti-angiogenesis, inducing ROS production, DNA strand breakage and cell apoptosis.

Bisdemethoxycurcumin is a natural curcumin derivative that activates the AMPKα pathway to attenuate LPS-induced acute lung injury; reversibly inhibits tyrosinase and possesses anti-browning ability; enhances the antiprostate cancer efficacy of docetaxel (DTX); targets cellular pathways involved in oxidative stress and apoptosis; and is an anticancer agent.

7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD).

Diarylcomosol III shows inhibitory effects on melanogenesis in B16 melanoma cells, it is a promising therapeutic agent for the treatment of skin disorders.

(4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).

7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) is a natural product for research related to life sciences. The catalog number is TN3217 and the CAS number is 79559-60-7.

Bisacurone C is a natural product from Curcuma longa.

Selina-4(15),7(11)-dien-8-one is a natural product for research related to life sciences. The catalog number is TN3467 and the CAS number is 54707-47-0.

Curcumaromin B is a natural product from Curcuma aromatica Salisb.

(3R,5R)-3,5-dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptane may have anti-adipogenic activity.

5"-Methoxyhexahydrocurcumin is a natural product for research related to life sciences. The catalog number is TN5656 and the CAS number is 138870-96-9.

Curcumenone may have protective effect on drunkenness, through increasing liver alcohol dehydrogenase activity.

1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one exhibits strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation in human whole blood.

Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B).