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Compound Libraries Target / Pathway Focused

Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No. product name
L4800 Angiogenesis related Compound Library A unique collection of 1370 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); 1370 compounds
L7200 Calcium Antagonist Library A unique collection of 143 calcium channel blockers and agonists for high throughput and high content screening; 143 compounds
L2800 Serotonin Receptor-Targeted Compound Library A unique collection of 275 compounds targeting serotonin receptors for high throughput screening and high content screening; 275 compounds
L8600 Ubiquitination Compound Library A unique collection of 214 ubiquitination related small chemicals can be used for high throughput and high content screening; 214 compounds
L3600 Cytokine Inhibitor Library A unique collection of 448 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; 448 compounds
L1580 GPCR Compound Library Plus Quantity: well-chosen 403 GPCR targeting compounds with unique structures; 403 compounds
L2300 Ion Channel Inhibitor Library A unique collection of 946 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; 946 compounds
L9700 Endoplasmic Reticulum Stress Compound Library 193 compounds
L9420 Exosome Compound Library 54 compounds
L3510 Methylation Compound Library 131 compounds
L3700 JAK-STAT Compound Library A unique collection of 256 JAK/STAT signaling targeted compounds for high throughput and high content screening; 256 compounds
L1600 Kinase Inhibitor Library A unique collection of 2160 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; 2160 compounds
L7600 Chemokine Inhibitor Library A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; 59 compounds
L2610 Neurotransmitter Receptor Compound Library A unique collection of 1290 neurotransmitter receptor compounds, can be used for HTS and HCS screening; 1290 compounds
L1100 Protease Inhibitor Library A unique collection of 637 protease and proteasome inhibitors for research in chemical genomics, and drug screening; 637 compounds
L1120 AMPK-Targeted Compound Library 64 compounds
L7400 Sodium Channel Blocker Library A unique collection of 128 sodium channel blockers and agonists for high throughput and high content screening; 128 compounds
L7300 Potassium Channel Blocker Library A unique collection of 160 potassium channel blockers and agonists for high throughput and high content screening; 160 compounds
L8100 Cell Cycle Compound Library A unique collection of 695 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); 695 compounds
L1510 Nuclear Receptor Inhibitor Library A unique collection of 420 nuclear receptor signaling targeted compounds for high throughput and high content screening; 420 compounds
L4100 TGF-beta/Smad Compound Library A unique collection of 180 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; 180 compounds
L1500 GPCR Compound Library A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; 1633 compounds
L2700 Adrenergic Receptor-Targeted Compound Library A unique collection of 219 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; 219 compounds
L8700 Ferroptosis Compound Library A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; 800 compounds
L5300 Mitochondria-Targeted Compound Library A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; 447 compounds
L2000 Inhibitor Library A unique collection of 5700 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; 5700 compounds
L1200 Epigenetics Compound Library Quantity: well-chosen 1120 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; 1120 compounds
L2200 Tyrosine Kinase Inhibitor Library A unique collection of 747 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; 747 compounds
L1300 PI3K-AKT-mTOR Compound Library A unique collection of 425 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; 425 compounds
L4300 Wnt/Hedgehog/Notch Compound Library A unique collection of 240 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; 240 compounds
L8500 HIF-1 Signaling Pathway Compound Library A unique collection of 1353 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; 1353 compounds
L3900 DNA Damage & Repair Compound Library A unique collection of 937 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); 937 compounds
L3300 Histamine & Melatonin Receptor-Targeted Compound Library A unique collection of 155 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; 155 compounds
L3800 NF-κB Signaling Compound Library A unique collection of 560 compounds targeting NF-κB signaling for high throughput screening and high content screening; 560 compounds
L3200 Autophagy Compound Library A unique collection of 1248 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; 1248 compounds
L1400 MAPK Inhibitor Library A unique collection of 367 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; 367 compounds
L9100 Phosphatase Inhibitor Library A collection of 80 phosphatase inhibitors with known activity; 80 compounds
L2600 Neuronal Signaling Compound Library A unique collection of 2011 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; 2011 compounds
L9000 Apoptosis Compound Library A unique collection of 1797 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; 1797 compounds
Angiogenesis related Compound Library
L4800 compounds - 1370
Calcium Antagonist Library
L7200 compounds - 143
Serotonin Receptor-Targeted Compound Library
L2800 compounds - 275
Ubiquitination Compound Library
L8600 compounds - 214
Cytokine Inhibitor Library
L3600 compounds - 448
GPCR Compound Library Plus
L1580 compounds - 403
Ion Channel Inhibitor Library
L2300 compounds - 946
Endoplasmic Reticulum Stress Compound Library
L9700 compounds - 193
Exosome Compound Library
L9420 compounds - 54
Methylation Compound Library
L3510 compounds - 131
JAK-STAT Compound Library
L3700 compounds - 256
Kinase Inhibitor Library
L1600 compounds - 2160
Chemokine Inhibitor Library
L7600 compounds - 59
Neurotransmitter Receptor Compound Library
L2610 compounds - 1290
Protease Inhibitor Library
L1100 compounds - 637
AMPK-Targeted Compound Library
L1120 compounds - 64
Sodium Channel Blocker Library
L7400 compounds - 128
Potassium Channel Blocker Library
L7300 compounds - 160
Cell Cycle Compound Library
L8100 compounds - 695
Nuclear Receptor Inhibitor Library
L1510 compounds - 420
TGF-beta/Smad Compound Library
L4100 compounds - 180
GPCR Compound Library
L1500 compounds - 1633
Adrenergic Receptor-Targeted Compound Library
L2700 compounds - 219
Ferroptosis Compound Library
L8700 compounds - 800
Mitochondria-Targeted Compound Library
L5300 compounds - 447
Inhibitor Library
L2000 compounds - 5700
Epigenetics Compound Library
L1200 compounds - 1120
Tyrosine Kinase Inhibitor Library
L2200 compounds - 747
PI3K-AKT-mTOR Compound Library
L1300 compounds - 425
Wnt/Hedgehog/Notch Compound Library
L4300 compounds - 240
HIF-1 Signaling Pathway Compound Library
L8500 compounds - 1353
DNA Damage & Repair Compound Library
L3900 compounds - 937
Histamine & Melatonin Receptor-Targeted Compound Library
L3300 compounds - 155
NF-κB Signaling Compound Library
L3800 compounds - 560
Autophagy Compound Library
L3200 compounds - 1248
MAPK Inhibitor Library
L1400 compounds - 367
Phosphatase Inhibitor Library
L9100 compounds - 80
Neuronal Signaling Compound Library
L2600 compounds - 2011
Apoptosis Compound Library
L9000 compounds - 1797