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Compound Libraries Target / Pathway Focused

Target / Pathway Focused

A target-focused library is a screening collection of compounds specifically tailored to modulate the function of a particular target or a protein family. These libraries not only reduce waste by eliminating compounds that are unlikely to bind to target proteins, but often lead to the increased potency and specificity of binders, as demonstrated for c-Src kinase. Compared to large and diverse screening libraries, using relatively small and targeted collections significantly improves the odds of finding potential drug candidates, thus further reduces the costs of drug discovery.

Cat No. product name
L4800 Angiogenesis related Compound Library A unique collection of 504 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS); 504 compounds
L7200 Calcium Antagonists Library A unique collection of 75 calcium channel blockers and agonists for high throughput and high content screening; 75 compounds
L2800 Serotonin Compound Library A unique collection of 170 compounds targeting serotonin receptors for high throughput screening and high content screening; 170 compounds
L8600 Ubiquitination Compound Library A unique collection of 95 ubiquitination related small chemicals can be used for high throughput and high content screening; 95 compounds
L3600 Cytokine Inhibitor Library A unique collection of 182 compounds targeting cytokine signaling for high throughput screening and high content screening for drug discovery; 182 compounds
L1580 GPCR Library Plus Quantity: well-chosen 403 GPCR targeting compounds with unique structures; 403 compounds
L2300 Ion Channel Inhibitor Library A unique collection of 705 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery; 705 compounds
L9420 Exosome Related Compound Library 45 compounds
L9700 Endoplasmic Reticulum Stress Compound Library 155 compounds
L3510 Methylation Compound Library 125 compounds
L3700 JAK STAT Compound Library A unique collection of 218 JAK/STAT signaling targeted compounds for high throughput and high content screening; 218 compounds
L2610 Neurotransmitter Receptor Compound Library A unique collection of 956 neurotransmitter receptor compounds, can be used for HTS and HCS screening; 956 compounds
L1100 Protease Inhibitor Library A unique collection of 295 protease and proteasome inhibitors for research in chemical genomics, and drug screening; 295 compounds
L1120 AMPK-Targeted Compound Library 36 compounds
L8100 Cell cycle related Compound Library A unique collection of 302 cell cycle related compounds for high throughput screening (HTS) and high content screening (HCS); 302 compounds
L1600 Kinase Inhibitor Library A unique collection of 2203 kinase inhibitors for high throughput screening and high content screening for drug discovery in kinase related diseases; 2203 compounds
L7600 Chemokine inhibitors Library A unique collection of 35 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; 35 compounds
L7400 Sodium Channel Blockers Library A unique collection of 62 sodium channel blockers and agonists for high throughput and high content screening; 62 compounds
L7300 Potassium Channel Blockers Library A unique collection of 90 potassium channel blockers and agonists for high throughput and high content screening; 90 compounds
L1510 Nuclear-receptor Inhibitors Library A unique collection of 298 nuclear receptor signaling targeted compounds for high throughput and high content screening; 298 compounds
L1500 GPCR Compound Library A unique collection of 1473 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; 1473 compounds
L2700 Adrenergic Receptor Compound Library A unique collection of 117 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; 117 compounds
L8700 Ferroptosis Compound Library A unique collection of 694 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study; 694 compounds
L5300 Mitochondrial Targeting Compound Library A unique collection of 168 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; 168 compounds
L1300 PI3K-AKT-mTOR Compound Library A unique collection of 319 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved with PI3K/Akt/mTOR signaling; 319 compounds
L4300 Wnt&Hedgehog&Notch Compound Library A unique collection of 136 Wnt/Hedgehog/Notch signaling targeted compounds for high throughput and high content screening; 136 compounds
L3300 Histamine & Melatonin Library A unique collection of 120 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; 120 compounds
L4100 TGF-beta/Smad Compound Library A unique collection of 116 TGF-beta/Smad signaling targeted compounds for high throughput and high content screening; 116 compounds
L2000 Inhibitor Library A unique collection of 4784 inhibitors for research in cell signaling, high throughput screening (HTS) and high content screening (HCS) for new drugs; 4784 compounds
L1200 Epigenetics Compound Library Quantity: well-chosen 1016 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; 1016 compounds
L2200 Tyrosine kinase inhibitor library A unique collection of 640 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related diseases; 640 compounds
L8500 HIF-1 Signaling Pathway Compound Library A unique collection of 1071 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; 1071 compounds
L3900 DNA Damage & Repair Compound Library A unique collection of 773 DNA Damage & Repair related compounds for high throughput screening (HTS) and high content screening (HCS); 773 compounds
L3800 NF-κB Signaling Compound Library A unique collection of 452 compounds targeting NF-κB signaling for high throughput screening and high content screening; 452 compounds
L1400 MAPK Inhibitor Library A unique collection of 234 compounds targeting MAPK signaling for drug discovery in MAPK related diseases; 234 compounds
L3200 Autophagy Compound Library A unique collection of 1067 compounds with defined autophagy-inducing or -inhibitory activity for research in autophagy, high throughput screening (HTS) and high content screening (HCS) for new drugs; 1067 compounds
L9100 Phosphatase Inhibitor Library A collection of 39 phosphatase inhibitors with known activity; 39 compounds
L2600 Neuronal Signaling Compound Library A unique collection of 1740 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs; 1740 compounds
L9000 Apoptosis Compound Library A unique collection of 1383 apoptosis-related compounds for apoptosis research, research in tumorigenesis, and anti-cancer drug screening; 1383 compounds
Angiogenesis related Compound Library
L4800 compounds - 504
Calcium Antagonists Library
L7200 compounds - 75
Serotonin Compound Library
L2800 compounds - 170
Ubiquitination Compound Library
L8600 compounds - 95
Cytokine Inhibitor Library
L3600 compounds - 182
GPCR Library Plus
L1580 compounds - 403
Ion Channel Inhibitor Library
L2300 compounds - 705
Exosome Related Compound Library
L9420 compounds - 45
Endoplasmic Reticulum Stress Compound Library
L9700 compounds - 155
Methylation Compound Library
L3510 compounds - 125
JAK STAT Compound Library
L3700 compounds - 218
Neurotransmitter Receptor Compound Library
L2610 compounds - 956
Protease Inhibitor Library
L1100 compounds - 295
AMPK-Targeted Compound Library
L1120 compounds - 36
Cell cycle related Compound Library
L8100 compounds - 302
Kinase Inhibitor Library
L1600 compounds - 2203
Chemokine inhibitors Library
L7600 compounds - 35
Sodium Channel Blockers Library
L7400 compounds - 62
Potassium Channel Blockers Library
L7300 compounds - 90
Nuclear-receptor Inhibitors Library
L1510 compounds - 298
GPCR Compound Library
L1500 compounds - 1473
Adrenergic Receptor Compound Library
L2700 compounds - 117
Ferroptosis Compound Library
L8700 compounds - 694
Mitochondrial Targeting Compound Library
L5300 compounds - 168
PI3K-AKT-mTOR Compound Library
L1300 compounds - 319
Wnt&Hedgehog&Notch Compound Library
L4300 compounds - 136
Histamine & Melatonin Library
L3300 compounds - 120
TGF-beta/Smad Compound Library
L4100 compounds - 116
Inhibitor Library
L2000 compounds - 4784
Epigenetics Compound Library
L1200 compounds - 1016
Tyrosine kinase inhibitor library
L2200 compounds - 640
HIF-1 Signaling Pathway Compound Library
L8500 compounds - 1071
DNA Damage & Repair Compound Library
L3900 compounds - 773
NF-κB Signaling Compound Library
L3800 compounds - 452
MAPK Inhibitor Library
L1400 compounds - 234
Autophagy Compound Library
L3200 compounds - 1067
Phosphatase Inhibitor Library
L9100 compounds - 39
Neuronal Signaling Compound Library
L2600 compounds - 1740
Apoptosis Compound Library
L9000 compounds - 1383