T13182 |
Toll-like receptor modulator
|
926927-42-6
|
98%
|
|
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TP2282L |
Pam2CSK4 TFA
|
|
98%
|
|
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, an...
|
TP1938 |
RS 09
|
1449566-36-2
|
98%
|
|
TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enh...
|
T10437 |
AZD8848
|
866269-28-5
|
98%
|
|
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
|
T13168 |
TLR7 agonist 1
|
2178156-33-5
|
98%
|
|
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
|
T16870 |
Selgantolimod
|
2004677-13-6
|
98%
|
|
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
|
T14035 |
3M-011
|
642473-62-9
|
98%
|
|
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
|
T38635 |
Kdo2-Lipid A ammonium
|
1246298-62-3
|
98%
|
|
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
|
T72035 |
TLR7/8/9 antagonist 2
|
2920729-91-3
|
98%
|
|
TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. TLR7/8/9 antagonist 2 inhibits HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC...
|
TN5138 |
Teuclatriol
|
152110-17-3
|
98%
|
|
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
|
T15751 |
LHC-165
|
1258595-14-0
|
98%
|
|
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
|
T15017 |
CU-T12-9
|
1821387-73-8
|
99.93%
|
|
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines...
|
T13167 |
TLR7/8 agonist 3
|
642473-95-8
|
99.93%
|
|
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.
|
T6846 |
Vesatolimod
|
1228585-88-3
|
99.92%
|
|
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
|
T0951 |
Hydroxychloroquine sulfate
|
747-36-4
|
99.87%
|
|
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
|
T38078 |
TLR7/8-IN-1
|
2205095-75-4
|
99.80%
|
|
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1].
|
T6964 |
Resiquimod
|
144875-48-9
|
99.78%
|
|
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effe...
|
T72253 |
AXC-715 trihydrochloride
|
2479276-17-8
|
99.74%
|
|
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly p...
|
T5521 |
Bropirimine
|
56741-95-8
|
99.74%
|
|
Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
|