T35349 |
CU-CPD107
|
2573912-32-8
|
98%
|
|
|
T13182 |
Toll-like receptor modulator
|
926927-42-6
|
98%
|
|
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
|
T13168 |
TLR7 agonist 1
|
2178156-33-5
|
98%
|
|
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
|
T10437 |
AZD8848
|
866269-28-5
|
98%
|
|
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
|
T15751 |
LHC-165
|
1258595-14-0
|
98%
|
|
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
|
T15785 |
LPA1 receptor antagonist 1
|
1396006-71-5
|
98%
|
|
LPA1 antagonist 1 is a highly selective Lysophosphatidic Acid receptor-1 (LPA1) antagonist (IC50: 25 nM).
|
T16870 |
Selgantolimod
|
2004677-13-6
|
98%
|
|
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
|
TP1938 |
RS 09
|
1449566-36-2
|
98%
|
|
TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enh...
|
T17032 |
Telratolimod
|
1359993-59-1
|
98%
|
|
Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
|
TN4171 |
Grossamide
|
80510-06-1
|
98%
|
|
Grossamide possesses potential anti-inflammatory effects, it also has potential anti-neuroinflammatory effects against lipopolysaccharide (LPS)-induced inflammat...
|
T14035 |
3M-011
|
642473-62-9
|
98%
|
|
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
|
TN5138 |
Teuclatriol
|
152110-17-3
|
98%
|
|
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
TJS1779 |
Protosappanin A
|
102036-28-2
|
98%
|
|
Protosappanin A has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammat...
|
T19675 |
SM360320
|
226907-52-4
|
98%
|
|
SM360320 is an effective and selective agonist of TLR7. SM360320 inhibits HCV replication in hepatocytes via a type I IFN-independent mechanism in addition to it...
|
T9570 |
Enpatoran
|
2101938-42-3
|
98%
|
|
Enpatoran is an inhibitor of TLR7(IC50 = 11.1 nM) and TLR8(IC50 = 24.1 nM). Enpatoran was found to be inactive against TLR3, TLR4, and TLR9 in vitro and in vivo....
|
T60052 |
BMS-905
|
2205846-49-5
|
98%
|
|
BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatm...
|
T37292 |
M62812
|
613263-00-6
|
98%
|
|
TLR4 inhibitor. Inhibits LPS-induced NF-κB activation in HEK293 cells (IC50 = 2.4 μg/mL). Also inhibits LPS-induced cytokine production and procoagulant effects ...
|
T39669 |
TLR7/8/9-IN-1
|
2180127-82-4
|
98%
|
|
TLR7/8/9-IN-1 is a potent inhibitor of Toll-like receptors 7/8/9 (TLR7/8/9) with an IC50 of 43 nM.
|
T39654 |
Afimetoran
|
2171019-55-7
|
98%
|
|
Afimetoran is a toll-like receptor antagonist. Afimetoran can be used in the research of inflammatory and autoimmune diseases.
|