Home Tools
Log in
Cart

TLR

Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are single-pass membrane-spanning receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T13182 Toll-like receptor modulator 926927-42-6 98%
Toll-like receptor modulator
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
TN3587 Capillarisin 56365-38-9 98%
Capillarisin
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
TP2282L Pam2CSK4 TFA 98%
Pam2CSK4 TFA
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, an...
TP1938 RS 09 1449566-36-2 98%
RS 09
TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enh...
T10437 AZD8848 866269-28-5 98%
AZD8848
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
T13168 TLR7 agonist 1 2178156-33-5 98%
TLR7 agonist 1
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
T16870 Selgantolimod 2004677-13-6 98%
Selgantolimod
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
T14035 3M-011 642473-62-9 98%
3M-011
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
T38635 Kdo2-Lipid A ammonium 1246298-62-3 98%
Kdo2-Lipid A ammonium
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
T72035 TLR7/8/9 antagonist 2 2920729-91-3 98%
TLR7/8/9 antagonist 2
TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. TLR7/8/9 antagonist 2 inhibits HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC...
TN5138 Teuclatriol 152110-17-3 98%
Teuclatriol
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
T15751 LHC-165 1258595-14-0 98%
LHC-165
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
T15017 CU-T12-9 1821387-73-8 99.93%
CU-T12-9
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines...
T13167 TLR7/8 agonist 3 642473-95-8 99.93%
TLR7/8 agonist 3
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.
T6846 Vesatolimod 1228585-88-3 99.92%
Vesatolimod
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
T0951 Hydroxychloroquine sulfate 747-36-4 99.87%
Hydroxychloroquine sulfate
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
T38078 TLR7/8-IN-1 2205095-75-4 99.80%
TLR7/8-IN-1
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1].
T6964 Resiquimod 144875-48-9 99.78%
Resiquimod
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effe...
T72253 AXC-715 trihydrochloride 2479276-17-8 99.74%
AXC-715 trihydrochloride
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly p...
T5521 Bropirimine 56741-95-8 99.74%
Bropirimine
Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
Toll-like receptor modulator
T13182
Toll-like receptor modulator is a TLR7/8 modulator, which modulates immune function.
Capillarisin
TN3587
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
Pam2CSK4 TFA
TP2282L
Pam2CSK4 TFA (PUL-042 TFA) is a potent dual agonist of TLR2 and TLR6, a peptide that mimics bacterial lipoproteins.Pam2CSK4 TFA promotes platelet aggregation, an...
RS 09
TP1938
TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enh...
AZD8848
T10437
AZD8848 is a selective antedrug agonist of toll-like receptor 7 (TLR7). It is developed for the research of asthma and allergic rhinitis.
TLR7 agonist 1
T13168
TLR7 agonist 1 is a selective and oral TLR7 agonist (IC50: 90 nM).
Selgantolimod
T16870
Selgantolimod is an effective and selective toll-like receptor 8 agonists for the treatment of the hepatitis B virus and human immunodeficiency virus infection.
3M-011
T14035
3M-011 is a potent dual toll-like receptor TLR7/8 agonist and a cytokine inducer, it is also a potent adjuvant to radiotherapy that induces local and profound sy...
Kdo2-Lipid A ammonium
T38635
Kdo2-Lipid A ammonium (KLA) is a selective and potent TLR4 agonist, a lipopolysaccharide.Kdo2-Lipid A ammonium induces the release of TNF and PGE2.
TLR7/8/9 antagonist 2
T72035
TLR7/8/9 antagonist 2 is an orally active and highly bioavailable vTLR7/8/9 antagonist. TLR7/8/9 antagonist 2 inhibits HEK/hTLR7, HEK/hTLR8 and HEK/hTLR9 with IC...
Teuclatriol
TN5138
Teuclatriol was found to be one of the compounds responsible for the immunoinhibitory effect of Salvia mirzayanii, by inhibiting NF-κB signaling at doses of 312...
LHC-165
T15751
LHC-165 is an agonist of TLR7. It also has the potential to treat solid tumors.
CU-T12-9
T15017
CU-T12-9 is a potent TLR1/2 agonist(EC50 of 52.9 nM in HEK-Blue hTLR2 SEAP assay). It acts by activating the NFkB pathway, upregulating proinflammatory cytokines...
TLR7/8 agonist 3
T13167
TLR7/8 agonist 3 is a potent agonist of TLR7 and TLR8.
Vesatolimod
T6846
Vesatolimod (GS-9620) is an effective and specific orally active agonist of Toll-like receptor 7.
Hydroxychloroquine sulfate
T0951
Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malari...
TLR7/8-IN-1
T38078
TLR7/8-IN-1, a crystalline TLR7/TLR8 inhibitor obtained from patent WO2019220390 (compound 2b), is a valuable compound for autoimmune disease research[1].
Resiquimod
T6964
Resiquimod (R848) is an imidazoquinoline amine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effe...
AXC-715 trihydrochloride
T72253
AXC-715 trihydrochloride (T785 trihydrochloride) is a TLR7/TLR8 dual agonist for the synthesis of antibody-adjuvanted immunocouplings. The couplings are mostly p...
Bropirimine
T5521
Bropirimine (U-54461) (U-54461) is a biological response modifier that is thought to act through the induction of lymphokines.
1 2 3 4 5
TargetMol