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RAAS

The renin–angiotensin system (RAS), or renin–angiotensin–aldosterone system (RAAS), is a hormone system that regulates blood pressure and fluid and electrolyte balance, as well as systemic vascular resistance.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T19722 Benazeprilat 86541-78-8 98.35%
Benazeprilat
Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with...
T68171 Zabicipril 83059-56-7 98.31%
Zabicipril
Zabicipril is a novel orally available angiotensin-converting enzyme inhibitor, a prodrug with antihypertensive activity following in vivo de-esterification.
T27762 L-162,313 151488-11-8 98.31%
L-162,313
L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.
T1461 Candesartan 139481-59-7 98.28%
Candesartan
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
T8270 Deserpidine 131-01-1 98.27%
Deserpidine
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apo...
T5030 Zofenopril calcium 81938-43-4 98.25%
Zofenopril calcium
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
T28540 Ripisartan 148504-51-2 98.24%
Ripisartan
Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.
T7808 Alacepril 74258-86-9 98.19%
Alacepril
Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive
TP1187 C-Type Natriuretic Peptide (CNP) (1-22), human 127869-51-6 98%
C-Type Natriuretic Peptide (CNP) (1-22), human
C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.
T0180 Benazepril hydrochloride 86541-74-4 98%
Benazepril hydrochloride
Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril hydrochlorid...
T6067 PD 123319 130663-39-7 98%
PD 123319
PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.
T5701 OPHIOPOGONIN D 945619-74-9 98%
OPHIOPOGONIN D
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
T6133 Remodelin hydrobromide 1622921-15-6 98%
Remodelin hydrobromide
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
T2322 Fimasartan 247257-48-3 98%
Fimasartan
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administrati...
T6219 Azilsartan Medoxomil 863031-21-4 97.72%
Azilsartan Medoxomil
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults wi...
T1940 BTB06584 219793-45-0 97.6%
BTB06584
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising d...
TP2158 TRV-120027 TFA TP2158 97.45%
TRV-120027 TFA
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
T7686 Ramiprilat 87269-97-4 97.45%
Ramiprilat
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T25226 Ceronapril 111223-26-8 95.27%
Ceronapril
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
T4431 Olodanrigan 1316755-16-4 94.13%
Olodanrigan
Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG...
Benazeprilat
T19722
Benazeprilat(CGS 14831) is an orally active active metabolite of Benazepril.Benazeprilat has potent antihypertensive activity and can be used in combination with...
Zabicipril
T68171
Zabicipril is a novel orally available angiotensin-converting enzyme inhibitor, a prodrug with antihypertensive activity following in vivo de-esterification.
L-162,313
T27762
L-162,313 is an ANG II receptor agonist, a nonpeptide that mimics the biological actions of angiotensin II and induces an increase in MAP.
Candesartan
T1461
Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.
Deserpidine
T8270
Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apo...
Zofenopril calcium
T5030
Zofenopril calcium (SQ26991) is an antioxidant that acts as an angiotensin-converting enzyme inhibitor. ACE Zofenopril is a pro-drug designed to undergo metaboli...
Ripisartan
T28540
Ripisartan (UP-269-6) is a potent and specific angiotensin II receptor antagonist that inhibits angiotensin II-mediated sympathetic tachycardia responses.
Alacepril
T7808
Alacepril (DU-1219) is a relatively novel angiotensin-converting enzyme inhibitor, used as an antihypertensive
C-Type Natriuretic Peptide (CNP) (1-22), human
TP1187
C-Type Natriuretic Peptide (CNP) (1-22), human is the 1-22 fragment of C-Type Natriuretic Peptide.
Benazepril hydrochloride
T0180
Benazepril hydrochloride (CGS 14824A HCl) is an angiotensin-converting enzyme (ACE) inhibitor widely used in the therapy of hypertension. Benazepril hydrochlorid...
PD 123319
T6067
PD 123319 ((S)-(+)-PD 123319) is a potent, selective AT2 angiotensin II receptor antagonist.
OPHIOPOGONIN D
T5701
Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.
Remodelin hydrobromide
T6133
Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.
Fimasartan
T2322
Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administrati...
Azilsartan Medoxomil
T6219
Azilsartan Medoxomil (TAK-491) is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults wi...
BTB06584
T1940
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising d...
TRV-120027 TFA
TP2158
TRV120027 TFA is a β-arrestin-1-biased agonist of the angiotensin II receptor type 1 (AT1R) and engages ß-arrestins while blocking G-protein signaling.
Ramiprilat
T7686
Ramiprilat is an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
Ceronapril
T25226
Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.
Olodanrigan
T4431
Olodanrigan (EMA401), a highly selective AT2R antagonist, inhibition of augmented AngII/AT2R induced p38 and p42/p44 MAPK activation, and hence inhibition of DRG...
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TargetMol