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Pyroptosis

Pyroptosis, also known as cell inflammatory necrosis, is a kind of programmed cell death, the performance of the cell swelling until the rupture of the cell membrane, resulting in the release of cell contents and activate a strong inflammatory response.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T79743 Caspase-3 activator 1 98%
Caspase-3 activator 1
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This clea...
T74923 ICy-Q 2863682-83-9 98%
ICy-Q
ICy-Q, a near-infrared (NIR) reagent activated by quinone oxidoreductase 1 (NQO-1), interacts with NQO-1 to yield the reduced product ICy-OH. This derivative sel...
T3414 Morroniside 25406-64-8 99.84%
Morroniside
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal ...
T6S2315 Polyphyllin VI 55916-51-3 99.69%
Polyphyllin VI
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
T11828 LDC7559 2407782-01-6 99.47%
LDC7559
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
T36347 Ac-YVAD-CMK 178603-78-6 97.08%
Ac-YVAD-CMK
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
T0054 Disulfiram 97-77-8 95%
Disulfiram
Disulfiram (NSC-190940) is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alter...
Caspase-3 activator 1
T79743
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This clea...
ICy-Q
T74923
ICy-Q, a near-infrared (NIR) reagent activated by quinone oxidoreductase 1 (NQO-1), interacts with NQO-1 to yield the reduced product ICy-OH. This derivative sel...
Morroniside
T3414
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal ...
Polyphyllin VI
T6S2315
1. Polyphyllin VI has hemostasis , expectorant , bacteriostasis, anticytotoxic, anti pregnancy kill sperm effects.
LDC7559
T11828
LDC7559 inhibits gasdermin D (GSDMD) by blocking neutrophil extracellular trap (NET) at late stage.
Ac-YVAD-CMK
T36347
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprot...
Disulfiram
T0054
Disulfiram (NSC-190940) is a carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alter...
TargetMol