TN3517 |
Bisacurone
|
120681-81-4
|
98%
|
|
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
|
TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
TN3726 |
Cudraflavone B
|
19275-49-1
|
98%
|
|
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
|
TN2534 |
1-Hydroxy-2,3,5-trimethoxyxanthone
|
22804-49-5
|
98%
|
|
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
|
TN4383 |
Kazinol U
|
1238116-48-7
|
98%
|
|
Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces ce...
|
T11633 |
IKK-IN-1
|
406211-06-1
|
98%
|
|
IKK-IN-1 is an inhibitor of IKK.
|
TN3486 |
Bakkenolide IIIa
|
915289-60-0
|
98%
|
|
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB...
|
T10472L |
Bay 65-1942 free base
|
600734-02-9
|
98%
|
|
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
|
T2S0606 |
Bakkenolide A
|
19906-72-0
|
98%
|
|
Bakkenolide A has antifeedant and growth inhibitory effects on neonate variegated cutworms, it inhibits leukemia by regulation of HDAC3 and PI3K/Akt-related sign...
|
TN4779 |
Physalin O
|
120849-18-5
|
98%
|
|
Physalin O possesses anti-inflammatory activity, it exhibited conjugating abilities with GSH and also showed significant nitric oxide (NO) production inhibiting ...
|
TN3219 |
7,8-Didehydrocimigenol
|
150972-72-8
|
98%
|
|
7,8-Didehydrocimigenol can be used for the treatment of cardiovascular disorders such as atherosclerosis. It upregulates PPAR-γ in EC inhibits NF-kB activity of ...
|
T13097 |
TBK1/IKKε-IN-1
|
2058264-32-5
|
98%
|
|
TBK1/IKKε-IN-1 is a dual inhibitor of TBK1 and IKKε (IC50s of <100 nM).
|
TN3614 |
Cearoin
|
52811-37-7
|
98%
|
|
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4162 |
Goshonoside F5
|
90851-28-8
|
98%
|
|
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
T14508 |
Bay 65-1942 hydrochloride
|
600734-06-3
|
98%
|
|
Bay 65-1942 hydrochloride is an inhibitor of ATP-competitive and selective IKKβ.
|
TN4318 |
Isophysalin A
|
1363398-67-7
|
98%
|
|
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production in...
|
T14669 |
BMS-066
|
914946-88-6
|
98%
|
|
BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.
|
T14567 |
BI605906
|
960293-88-3
|
98%
|
|
BI605906 is an inhibitor of IKKβ. When assayed at 0.1 mM ATP, the IC50 value is 380 nM.
|