TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
TN3486 |
Bakkenolide IIIa
|
915289-60-0
|
98%
|
|
Bakkenolide IIIa has antioxidant, and neuroprotective effects, it protects against cerebral damage by inhibiting AKT and ERK1/2 activation and inactivated NF-κB...
|
TN3614 |
Cearoin
|
52811-37-7
|
98%
|
|
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
|
TN3517 |
Bisacurone
|
120681-81-4
|
98%
|
|
Bisacurone has anti-oxidant, anti-inflammatory, and anti-metastatic activities, it may have a protective effect against ethanol-induced liver injury by suppressi...
|
T12659 |
(Rac)-BAY-985
|
2101925-20-4
|
98%
|
|
(Rac)-BAY-985 is a potent, ATP-competitive and selective inhibitor of TBK1(IC50 of 1.5 nM),with antitumor efficacy.
|
TN3726 |
Cudraflavone B
|
19275-49-1
|
98%
|
|
Cudraflavone B has anti-proliferative activity, mouse brain monoamine oxidase (MAO) inhibitory effects, apoptotic actions in human gastric carcinoma cells and mo...
|
TN4162 |
Goshonoside F5
|
90851-28-8
|
98%
|
|
Goshonoside F5 has anti-inflammatory activity, it significantly inhibits the pro-inflammatory response induced by LPS, both in vitro and in vivo.
|
T10472L |
Bay 65-1942 free base
|
600734-02-9
|
98%
|
|
Bay 65-1942 free base is an inhibitor of ATP-competitive and selective IKKβ.
|
T14567 |
BI605906
|
960293-88-3
|
98%
|
|
BI605906 is an inhibitor of IKKβ. When assayed at 0.1 mM ATP, the IC50 value is 380 nM.
|
TN4420 |
Latifolin
|
10154-42-4
|
98%
|
|
Latifolin is a strong DPPH-scavenger, it attenuates inflammatory responses by inhibiting NF-κB activation via Nrf2-mediated heme oxygenase-1 expression. Latifol...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4779 |
Physalin O
|
120849-18-5
|
98%
|
|
Physalin O possesses anti-inflammatory activity, it exhibited conjugating abilities with GSH and also showed significant nitric oxide (NO) production inhibiting ...
|
TN3539 |
Broussonin A
|
73731-87-0
|
98%
|
|
Broussonins A and B, new phytoalexins from diseased paper mulberry. Broussonin A shows estrogenic activity with ligand-binding activity of estrogen receptor, tra...
|
TN4383 |
Kazinol U
|
1238116-48-7
|
98%
|
|
Kazinol U may have therapeutic value in delaying pancreatic β-cell destruction in type 1 diabetes by blocking the NF-κB pathway in pancreatic β-cells reduces ce...
|
TN4318 |
Isophysalin A
|
1363398-67-7
|
98%
|
|
Isophysalin A exhibits anti-inflammatory activitiy, it exhibits conjugating abilities with glutathione and also shows significant nitric oxide (NO) production in...
|
TN4683 |
Nyasol
|
96895-25-9
|
98%
|
|
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory ...
|
TN2534 |
1-Hydroxy-2,3,5-trimethoxyxanthone
|
22804-49-5
|
98%
|
|
1-Hydroxy-2,3,5-trimethoxyxanthone (HM-1) has vasodilator action ,which involves both an endothelium-dependent mechanism involving NO and an endothelium-independ...
|
T15558 |
GSK319347A
|
862812-98-4
|
98%
|
|
GSK319347A is a TBK1 and IKKε dual inhibitor (IC50s: 93 nM and 469 nM, respectively). GSK319347A inhibits IKK2 (IC50: 790 nM).
|
TN4986 |
Selinidin
|
19427-82-8
|
98%
|
|
Selinidin decreases phosphorylation of phospholipase C-gamma1, p38 mitogen-activated protein kinase, and IkappaB-alpha upon FcepsilonRI stimulation.
|