T11280 |
FGFR4-IN-4
|
2230973-67-6
|
98%
|
|
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
|
T6036 |
Brivanib
|
649735-46-6
|
98%
|
|
Brivanib is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
|
T13003 |
SSR128129E free acid
|
848463-13-8
|
98%
|
|
SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1).
|
T35331 |
Dovitinib (TKI258) Lactate
|
|
98%
|
|
|
T3512 |
S49076 HCl
|
1265966-31-1
|
98%
|
|
S49076 is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 potently blocked cellular phosphorylation of MET, AXL, and FGFRs and inhibited downstream...
|
T1991 |
ZM323881 hydrochloride
|
193000-39-4
|
98%
|
|
ZZZM 323881 hydrochloride is a potent and selective VEGFR2 inhibitor.
|
T16781 |
Rogaratinib
|
1443530-05-9
|
98%
|
|
Rogaratinib is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1...
|
T10870 |
CP-547632 hydrochloride
|
252003-71-7
|
98%
|
|
CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficac...
|
T10870L |
CP-547632
|
252003-65-9
|
98%
|
|
CP-547632 is a well-tolerated, orally-bioavailable inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50s: 11 nM and 9 nM) with antitum...
|
T8525 |
EGFR-IN-16
|
133550-22-8
|
98%
|
|
AG473 is an inhibitor of EGFR in human A431 cells.
|
T6193 |
Dovitinib Dilactic Acid
|
852433-84-2
|
98%
|
|
Dovitinib Dilactic acid (TKI258 Dilactic acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit) with ...
|
T27319 |
FIIN-4
|
2093088-81-2
|
98%
|
|
FIIN-4 is a covalent inhibitor of FGFR and can be used in studies about metastatic breast cancer.
|
T16364 |
Infigratinib phosphate
|
1310746-10-1
|
98%
|
|
Infigratinib phosphate is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
|
T2372L |
Ponatinib Hydrochloride
|
1114544-31-8
|
98%
|
|
Ponatinib Hydrochloride is a hydrochloride of ponatinib. Ponatinib is an orally active multi-targeted kinase inhibitor with IC50s of 0.37 nM, 1.1 nM, 1.5 nM, 2.2...
|
T13156L |
TG 100572 Hydrochloride
|
867331-64-4
|
98%
|
|
TG 100572 Hydrochloride is a inhibitor of multi-targeted kinase which inhibits receptor tyrosine kinases and Src kinases(IC50s of 2, 7, 2, 16, 13, 5, 0.5, 6, 0.1...
|
T1338 |
Sucralfate
|
54182-58-0
|
|
|
Sucralfate is a cytoprotective agent, an oral gastrointestinal medication primarily indicated for the treatment of active duodenal ulcers.
|
T19355 |
Heparan Sulfate
|
9050-30-0
|
|
|
Heparan Sulfate is a complex and linear polysaccharide, exists as part of glycoproteins named heparan sulfate proteoglycans, which are expressed abundantly on th...
|
T6154 |
SU11274
|
658084-23-2
|
|
|
SU11274(IC50=10 nM) is a specific Met inhibitor. It shows no significant effects on PGDFRβ, EGFR or Tie2.
|
T9030 |
SU4984
|
186610-89-9
|
100%
|
|
SU4984 is a cell-permeable, ATP-competitive and reversible inhibitor of the fibroblast growth factor receptor 1 (FGFR1).
|
T2S0007 |
Ferulic acid sodium
|
24276-84-4
|
100%
|
|
Sodium ferulate (SF), the sodium salt of ferulic acid, is a drug used in traditional Chinese medicine for treatment of cardiovascular and cerebrovascular disease...
|