Cat. No. | Product name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
T16781 | Rogaratinib | 1443530-05-9 | 99.54% |
|
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibi... | ||||
T3512 | S49076 HCl | 1265966-31-1 |
|
|
S49076 HCl (S-49076 Hydrochloride) is an effective inhibitor of MET, AXL/MER, and FGFR1/2/3. S49076 HCl potently blocked cellular phosphorylation of MET, AXL, an... | ||||
T78313 | Fazpilodemab | 2517935-02-1 | 98% |
Fazpilodemab
|
Fazpilodemab (BFKB8488A) is a humanized agonistic bispecific antibody that targets fibroblast growth factor receptor 1c (FGFR1c) and Klothoβ. It is utilized in r... | ||||
T78830 | FGFR1 inhibitor 7 | 98% |
|
|
FGFR1 Inhibitor 7 (compound 5), a potent FGFR1 tyrosine kinase inhibitor, exhibits an IC50 of 0.33 nM against its target and demonstrates broad-spectrum cytotoxi... | ||||
T78831 | FGFR1 inhibitor-8 | 98% |
|
|
FGFR1 inhibitor-8 (Compound 9), an FGFR1 inhibitor with an IC50 of 0.5 nM, binds to the ATP-binding pocket of FGFR1 and exhibits anticancer activity [1]. | ||||
T78832 | FGFR1 inhibitor-9 | 98% |
|
|
FGFR1 inhibitor-9 (Compound 7) is an FGFR1 inhibitor with potent binding affinity, exhibiting an IC50 of 0.85 nM. It targets the ATP-binding pocket of FGFR1 and ... | ||||
T79257 | FGFR-IN-11 | 2658488-68-5 | 98% |
|
FGFR-IN-11 (compound I-5) is an orally active, covalent inhibitor of FGFR, exhibiting IC50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (F... | ||||
T79271 | FGFR4-IN-14 | 98% |
|
|
FGFR4-IN-14 (Compound 27i) is a selective FGFR4 inhibitor with an IC50 of 2.4 nM, showing potent inhibition of cell proliferation in the V550L and N535K mutant s... | ||||
T79686 | FGFR1 inhibitor-10 | 2426769-76-6 | 98% |
|
FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation. This compound demonstrates anti-angiogenic and anti-invasion... | ||||
T79850 | Irpagratinib | 2230974-62-4 | 98% |
|
Irpagratinib (ABSK011) is an orally active fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor with specificity for FGFR4, exhibiting an IC50 of l... | ||||
T79856 | Resigratinib | 2750709-91-0 | 98% |
|
Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor exhibiting antineoplastic activity [1]. | ||||
T79871 | S6K2-IN-1 | 98% |
|
|
S6K2-IN-1 (Compound 2) is an inhibitor of S6K2 with an IC50 of 22 nM and also exhibits inhibitory activity against FGFR4 with an IC50 of 216 nM. This compound de... | ||||
T79880 | FGFR4-IN-16 | 1970120-44-5 | 98% |
|
FGFR4-IN-16 (CY-15-2) is a covalent inhibitor targeting FGFR-4, utilized in cancer research [1]. | ||||
T82404 | FGFR3-IN-7 | 2833703-79-8 | 98% |
|
FGFR3-IN-7 is a potent, selective inhibitor of FGFR 3, demonstrating an IC50 value of less than 350 nM , and is utilized in cancer research [1]. | ||||
T82405 | FGFR3-IN-6 | 2833703-72-1 | 98% |
|
FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1]. | ||||
T10870 | CP-547632 hydrochloride | 252003-71-7 | 98% |
|
CP-547632 hydrochloride is a well-tolerated and orally-bioavailable inhibitor of the VEGFR-2 and basic FGF kinases (IC50s: 11 nM and 9 nM) with antitumor efficac... | ||||
T13003 | SSR128129E free acid | 848463-13-8 | 98% |
|
SSR128129E free acid is an orally available and allosteric inhibitor of FGFR(IC50 of 1.9 μM for FGFR1). | ||||
T73121 | FGFR4-IN-8 | 2765240-52-4 | 98% |
|
FGFR4-IN-8 (Compound 7v) is an ATP-competitive inhibitor that covalently and highly selectively targets both the wild-type and gatekeeper mutant forms of FGFR4. ... | ||||
T11280 | FGFR4-IN-4 | 2230973-67-6 | 98% |
|
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity. | ||||
T6193 | Dovitinib Dilactic Acid | 852433-84-2 | 98% |
|
Dovitinib Dilactic Acid (Dovitinib (TKI-258) Dilactic Acid) is the Dilactic acid of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3... |