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zvae(ome)fmk

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Microtubule Inhibitor 185322
T715841027308-36-6
Microtubule inhibitor 185322 is an inhibitor of microtubule assembly, inducung mitotic arrest and apoptosis of MM cells.
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8-10 weeks
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Z-VAE(OMe)-fmk
T715861027141-02-1
Z-VAE(OMe)-fmk is a cell-permeable and irreversible UCHL1 inhibitor. The inhibitor approaches the active-site cleft from the opposite side of the crossover loop as compared to the direction of approach of ubiquitin's C-terminal tail, thereby occupying the P1' (leaving group) site, a binding site perhaps used by the unknown C-terminal extension of ubiquitin in the actual in vivo substrate(s) of UCHL1.
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6-8 weeks
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