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By Target- Histamine Receptor
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Results for "
zpl-3893787
" in TargetMol Product Catalog- Inhibitors & Agonists3
EphB1-IN-10
T699172097512-73-5
EphB1-IN-10 is a potent and selective covalent inhibitor of receptor tyrosine kinase EphB1.
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Adriforant
ZPL-3893797, ZPL3893797, ZPL-389, ZPL389, PF-3893787, PF3893787
T68280943057-12-3
Adriforant (PF-3893787,ZPL-3893797) is a competitive H4 (histamine receptor 4) antagonist that antagonizes histamine-induced phosphorylation of ERK, normalizes histamine-induced transcriptional changes in mast cells and reduces histamine-dependent Ca2+ fluxes in neurons, which alleviates itching and skin inflammation in mice
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Adriforant tartrate hydrate
T699182096455-87-5
Adriforant tartrate hydrate, also known as ZPL-3893787 tartrate hydrate, PF-3893787 tartrate hydrate and ZPL-389 tartrate hydrate, is a novel histamine H4 receptor antagonist. Adriforant tartrate hydrate shows an excellent in vitro profile that warrants their further investigation in relevant models of human disease. Histamine H4 receptor (H4R) has become a promising target for immuno-inflammatory diseases, such as allergic rhinitis, asthma or dermal allergies.
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