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(3)
By Target- Piezo Channel
- Akt(1)
- ERK(1)
- NO Synthase(1)
- Potassium Channel(1)
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Results for "
yoda1
" in TargetMol Product Catalog- Inhibitors & Agonists3
Yoda 1
Cited
T7506448947-81-7
Yoda 1 is an agonist of the Piezo1 channel that agonizes human- and mouse-derived Piezo1 (EC50=17.1/26.6 μM). Yoda 1 is also an inhibitor of glycine transporter protein 2 (GlyT2).
- $39
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QTY
CitedDooku1
T110762253744-54-4
Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yoda1-induced aortic relaxation.
- $38
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QTY
Yoda2
KC289
T2116833081450-95-2
Yoda2 (KC289), the potassium salt of Yoda1, is an agonist of PIEZO1 with an EC50 of 150 nM. It induces Ca2+ elevation in HeLa cells and can cause concentration-dependent and NO-dependent relaxation in mouse portal vein (EC50= 1.2 μM). Additionally, Yoda2 is capable of stimulating NOS3 and promoting NO production.
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