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By Target- Ligand for E3 Ligase
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Results for "
vhl ligand2
" in TargetMol Product Catalog- Inhibitors & Agonists2
- PROTAC Products2
(S,R,S)-AHPC-Me hydrochloride
VHL ligand 2 hydrochloride, E3 ligase Ligand 1
T136711948273-03-7
(S,R,S)-AHPC-Me hydrochloride (VHL ligand 2 hydrochloride) is utilized in the synthesis of ARV-771, a potent BET protein degrader. It selectively degrades BET protein in castration-resistant cells with a DC50 <1 nM. Recognized as VHL ligand 2 hydrochloride, it serves as the VHL ligand from (S,R,S)-AHPC for recruiting von Hippel-Lindau (VHL) protein.
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(S,R,S)-AHPC-Me
VHL ligand 2, E3 ligase Ligand 1A
T77521948273-02-6
(S,R,S)-AHPC-Me (E3 ligase Ligand 1A) (VHL ligand 2) is an (S,R,S)-AHPC-based VHL ligand used to recruit the von Hippel-Lindau (VHL) protein. It is utilized in the synthesis of ARV-771, a VHL E3 ligase-based BET PROTAC degrader that effectively degrades BET proteins in castration-resistant prostate cancer (CRPC) cells with a DC50 <1 nM.
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