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By Target- FLT
- TAM Receptor(2)
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Results for "
unc2025
" in TargetMol Product Catalog- Inhibitors & Agonists3
UNC2025
UNC-2025, UNC 2025, mrx-6313
T70071429881-91-3
UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER FLT3 inhibitor. UNC-2025 is about 20-fold selectivity higher than Axl and Tyro3.
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QTY
UNC2025 hydrochloride
UNC2025 hydrochloride
T394742070015-17-5
UNC2025 hydrochloride is a potent, ATP-competitive, highly orally active Mer Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM for Mer and Flt3, respectively. It demonstrates over 45-fold selectivity for MERTK compared to Axl (IC50 = 122 nM; Ki = 13.3 nM). Additionally, UNC2025 hydrochloride exhibits excellent PK properties, making it suitable for investigating acute leukemia.
Inquiry
UNC2025 2HCl (1429881-91-3(free base))
T4419
UNC2025 is a potent and orally bioavailable Mer Flt3 dual inhibitor with IC50 of 0.8 0.74 nM for Mer Flt3.
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