Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Histone Methyltransferase
    (1)
Filter
Search Result
Results for "

unc0642

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
UNC0642
UNC-0642, UNC 0642
T41661481677-78-4
UNC0642 is an effective and specific G9a GLP inhibitor (IC50< 2.5 nM).
  • Inquiry Price
Size
QTY
MS-8709
MS 8709, MS8709
T2024583060730-06-2
MS-8709 is a G9a GLP PROTAC Degrader (DC50(G9a) = 274 nM; DC50(GLP) = 260 nM) that induces G9a GLP degradation in a concentration-, time-, and ubiquitin-proteasome system (UPS)-dependent manner. It shows higher selectivity for G9a GLP over other methyltransferases, without affecting G9a GLP mRNA expression. In addition, MS-8709 demonstrates superior inhibition of prostate cancer, leukemia, and lung cancer cell growth compared to its parent compound, the G9a GLP inhibitor UNC0642, and possesses favorable murine pharmacokinetic properties for in vivo efficacy studies.
  • Inquiry Price
Size
QTY