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unc 2025 hydrochloride

" in TargetMol Product Catalog.
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  • UNC2025 hydrochloride
    UNC2025 hydrochloride
    T394742070015-17-5
    UNC2025 hydrochloride is a potent, ATP-competitive, highly orally active Mer/Flt3 inhibitor with IC50 values of 0.74 nM and 0.8 nM for Mer and Flt3, respectively. It demonstrates over 45-fold selectivity for MERTK compared to Axl (IC50 = 122 nM; Ki = 13.3 nM). Additionally, UNC2025 hydrochloride exhibits excellent PK properties, making it suitable for investigating acute leukemia.
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