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txb2 synthesis

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
Thiazinamium chloride
Multergan chloride
T131444320-13-2
Thiazinamium chloride possesses potent anticholinergic and antiallergic activity and inhibits synthesis of TxB2(IC50 value of 0.2 µM).
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6-8 weeks
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2,3-dinor Thromboxane B2
2,3-dinor TXB2
T8462663250-09-9
Thromboxane B2 (TXB2) is a compound significantly released from aggregating platelets and undergoes metabolic transformation during circulation into 11-dehydro TXB2 and 2,3-dinor TXB2. The latter, 2,3-dinor TXB2, serves as a prevalent urinary metabolite of TXB2 and acts as an indicator for in vivo TXA2 synthesis. Studies have shown that in healthy male volunteers, the median excretion rate of 2,3-dinor TXB2 is measured at 10.3 ng/hour, equivalent to 138 pg/mg of creatinine.
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8-10 weeks
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