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triparanol

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    TargetMol | Inhibitors_Agonists
Triparanol
MER-29, NSC 65345, NSC-65345, NSC65345
T2629678-41-1In house
Triparanol (NSC-65345) interferes with posttranslational modification of Hedgehog signaling molecules as well as the sterol sensing domain of its receptor PTCH1, leading to down-regulation of Hedgehog signaling. Triparanol suppresses human tumor growth and is an antilipemic agent with high ophthalmic toxicity.
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6-8 weeks
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