trientine-2hcl

Trientine-2HCl (Trien), a chelating agent, is used to treat Wilson's disease by binding up and removing copper in the body. Trientine can also be used as a chelating agent for copper in hepatolenticular degeneration, as a stabilizer for epoxy resins, and as ampholyte for isoelectric focusing.

TETA (tetraTFA) is an effective selective chelating agent for copper (II) ions. It is applicable in drug conjugation processes.

TETA hydrochloride hydrate is an effective and selective chelating agent for copper (II). It can be utilized in drug conjugation.

Triethylenetetramine (Trientine) tetrahydrochloride is an orally active, potent, and selective copper chelator. It aids in the excretion of divalent copper ions from the body, reduces intestinal copper absorption, and minimizes copper accumulation. Additionally, Triethylenetetramine tetrahydrochloride exhibits potential anticancer properties through mechanisms such as telomerase inhibition, anti-angiogenesis, and promoting cancer cell apoptosis (apoptosis). This compound shows promise in the study of Wilson's disease, cancer, and diabetic complications.

TETA, known as a macrocyclic chelator, has been attached to radioligands to facilitate PET imaging of neuroendocrine tumors and to conduct in vivo tissue distribution studies.