traumatic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T4454	Traumatic Acid	Dodec-2-Enedioic Acid,2E-Dodecenedioic Acid,Trans-2-Dodecenedioic Acid	Antioxidant
	Traumatic Acid (Dodec-2-Enedioic Acid) is a product of the hydroperoxide lyase pathway in plants. Potential as a wound healing agent that stimulates cell division near a wound site to form a protective callus.		Antioxidant
T2710	TCS 1102		OX Receptor
	TCS 1102 is an effective, dual orexin receptor antagonist (Ki: 0.2/3 nM for OX2/1 receptors).		OX Receptor
T3478	Ro 67-7476		GluR
	Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors. No activity at human mGlu1 receptors. Potentiates glutamate-induced calcium release with EC 50 of 60.1 nM.		GluR
T2371	Emapunil	AC-5216,XBD-173	Others
	Emapunil (XBD-173) is an anxiolytic drug which acts as a selective agonist at the peripheral benzodiazepine receptor, also known as the mitochondrial 18 kDa translocator protein or TSPO.		Others
T22323	Enoxaparin sodium		Thrombin
	Enoxaparin sodium is a low-molecular-weight heparin (LMWH) that has recently been approved by the US FDA for use in patients with medically managed ST-segment myocardial infarction (STEMI), or STEMI with subsequent percu...		Thrombin
T1461	Candesartan	CV 11974	RAAS
	Candesartan (CV 11974) is an angiotensin II receptor blocker used widely in the therapy of hypertension and heart failure.		RAAS
T33519	MTOB	α-keto-γ-Methylthiobutyric acid,KMBA,MTOB salt,4-methylthio 2-oxobutyric acid	Others
	MTOB (α-keto-γ-Methylthiobutyric acid) is a substrate for c-terminal binding protein (CtBP) that interferes with the carcinogenic activity of CtBP in cell culture and mice. It also actively regulates TCF-4 signaling, lea...		Others
T0183	Pramiracetam	CI-879	Others
	Pramiracetam (CI-879), derived from piracetam, is a more effective nootropic drug . According to reports, Pramiracetam improved cognitive defects related with traumatic brain wounds. Pramiracetam was also potent in the t...		Others
T77691	Cyclopentyl phenyl ketone	Benzoylcyclopentane	Others
	Cyclopentyl phenyl ketone (Benzoylcyclopentane) is used for the prevention and treatment of traumatic stress.		Others
T36857L	Premarin	Estrone 3-sulfate,Estrone sulfate	Estrogen Receptor/ERR
	Premarin (Estrone 3-sulfate) is an an estrogen sulfate with neuroprotective actions during traumatic brain injury.		Estrogen Receptor/ERR
T33535	MW01-2-151SRM	MW 151,MW-151,MW012151SRM,MW151,MW01 2 151SRM	Others
	MW01-2-151SRM is a novel small molecule inhibitor of microglia activation that crosses the blood-brain barrier, has anti-neuroinflammatory effects, attenuates the up-regulation of glial cytokines in models of neuroinflam...		Others
T13329	Vofopitant	GR 205171	Neurokinin receptor
	Vofopitant (GR 205171) is a potent NK1 receptor antagonist with anxiolytic and antiemetic activity for the study of post-traumatic stress disorder (PTSD).		Neurokinin receptor
T8807	Benzydamine		Others
	Benzydamine is a benzyl-indazole having analgesic, antipyretic, and anti-inflammatory effects. Benzydamine is used to reduce post-surgical and post-traumatic pain and edema and to promote healing.		Others
T10808	CHPG sodium salt		NF-κB , GluR
	CHPG sodium salt is a selective agonist of mGluR5 and activates the ERK and Akt signaling pathways. CHPG sodium salt can be used in studies about traumatic brain injury.		NF-κB , GluR
T22346	Indomethacin sodium hydrate	Indometacin sodium hydrate	COX
	Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,...		COX
T2698	Asperosaponin VI	Akebia saponin D,Asperosaponin Ⅵ	Apoptosis , Others , Caspase
	Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.		Apoptosis , Others , Caspase
T61934	Repinotan	BAY x 3702 free base	5-HT Receptor
	Repinotan (BAY x 3702 free base) is an orally active and selective 5-HT1A receptor agonist that crosses the blood-brain barrier (BBB), has neuroprotective activity, antagonizes morphine-induced depression of ventilation ...		5-HT Receptor
T1208	Citicoline sodium	Citicoline sodium salt,CDP-choline	Apoptosis , Others , Endogenous Metabolite
	Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demons...		Apoptosis , Others , Endogenous Metabolite
T4956	Tetrahydroxystilbene-2-O-β-D-glucoside	tetrahydroxyl diphenylethylene-2-o-gluco,EH-201	Others
	Tetrahydroxystilbene-2-O-β-D-glucoside (EH-201) is a low MW inducer of erythropoietin. Tetrahydroxystilbene-2-O-β-D-glucoside induces expression of erythropoietin, PPAR-γ coactivator 1α (PGC-1α) and haemoglobin in astroc...		Others
T34249	Rabeximod	ROB-803	TLR
	Rabeximod is a potent immunomodulator that reduces the severity of autoimmune diseases in rat models. Rabeximod inhibits arthritis in a time-dependent manner by stimulating TLR2 and TLR4 downstream to block the activatio...		TLR