trans-tamoxifen-d5

Tamoxifen-d5 is a deuterated form of Tamoxifen. Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen action in breast cells while activating estrogenic activity in other cells, such as those in bone, liver, and uterus. Tamoxifen is also a potent activator of Hsp90 and enhances the ATPase activity of the Hsp90 molecular chaperone.

Tamoxifen Citrate is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen activity in breast cells while activating estrogen signaling in cells such as those of the bone, liver, and uterus. As an Hsp90 activator, it enhances the ATPase activity of the Hsp90 chaperone complex, induces autophagy and apoptosis, and can be used to generate gene knockout models in CreER(T2) transgenic mice as well as liver injury models.

Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that acts as an estrogen antagonist in breast cells and an agonist in bone, liver, and uterine cells. It can be used to induce gene knockout and liver injury models in mice, and also exhibits multiple biological activities, including activation of Hsp90, induction of autophagy and apoptosis, and inhibition of EBOV and MARV viral infections.

Tamoxifen-D3 hydrochloride is a deuterium-labeled derivative of Tamoxifen (Citrate), which is an orally active selective estrogen receptor modulator (SERM). It inhibits estrogen activity in breast cells while activating estrogen receptors in other cells such as those in bone, liver, and uterus. Tamoxifen Citrate acts as a potent Hsp90 activator, enhancing the ATPase activity of the Hsp90 molecular chaperone. Furthermore, it effectively suppresses infectious EBOV Zaire and Marburg (MARV) viruses with IC50 values of 0.1 μM and 1.8 μM, respectively. Tamoxifen Citrate also stimulates autophagy and induces apoptosis, and is capable of triggering gene knockout in CreER (T2) transgenic mice.

Tamoxifen citrate (Standard) is the standard substance of Tamoxifen citrate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tamoxifen Citrate is an orally active selective estrogen receptor modulator (SERM) that blocks estrogen activity in breast cells while activating estrogen signaling in cells such as those of the bone, liver, and uterus. As an Hsp90 activator, it enhances the ATPase activity of the Hsp90 chaperone complex, induces autophagy and apoptosis, and can be used to generate gene knockout models in CreER(T2) transgenic mice as well as liver injury models.

Tamoxifen (Standard) is a reference standard of tamoxifen, suitable for quantitative analysis, quality control, and related research such as biochemical experiments. Tamoxifen is an orally active selective estrogen receptor modulator (SERM) that acts as an antagonist to estrogen in mammary cells and as an agonist in bone, liver, and uterine cells. Tamoxifen (Standard) can be used to induce gene knockout and liver injury models in mice, and possesses various biological activities, including the activation of Hsp90, inducing autophagy and apoptosis, and inhibiting EBOV (IC50 = 0.1 μM) and MARV (IC50 = 1.8 μM) viral infections.