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By Target- Acyltransferase
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Results for "
trans cm 414
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- F-1394T70356162490-89-3F-1394 is an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor. F-1394 both prevents the formation of atherosclerosis and accelerates its regression without affecting the serum TC level, indicating that F-1394 acts directly on the arterial wall. F-1394 significantly reduced neointimal thickening and the extent of macrophages in lesions without affecting serum cholesterol levels. In vitro, F-1394 attenuated foam cell formation in mouse peritoneal macrophages.
- $1,520
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