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tp3654

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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    TargetMol | Peptide_Products
TP-3654
T45231361951-15-6
TP-3654, a second-generation Pim kinase inhibitor (Ki values against Pim-1/3: 5/42 nM).
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(RXR)4XB
TP3654879010-15-8
(RXR)4XB is a cell-penetrating peptide that binds to phosphorodiamidate morpholino oligomer (PMO), resulting in a peptide-conjugated PMO (PPMO) and enhancing the delivery of PMO into bacterial cells. The (RXR)4XB-PMO conjugate prevents biofilm formation, inhibits Pseudomonas aeruginosa (with an MIC50 of 0.5-16 μM), and reduces bacterial load in a mouse acute pneumonia model.
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