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TOOS is a novel highly water-soluble aniline derivative and is widely used in diagnostic tests and biochemical tests.

1. Toosendanin possesses hepatotoxicity. 2. Toosendanin has effects on the growth, cell cycle arrest, induction of apoptosis and the involved signaling pathway in human promyelocytic leukemia HL-6 cells. 3. Toosendanin is an effective insecticide for Ae.

Isotoosendanin ((1S,2S,4R,5S,6R,9S,10S,11R,13R,18S,20R)-20-(acetyloxy)-6-(furan-3-yl)-11,15,18-trihydroxy-5,10,14-trimethyl-3,8-dioxo-16-oxapentacyclo[12.3.3.01,13.02,1?.0?,?]icosan-4-yl acetate) is a limonoid isolated from Melia toosendan fruit with anti-inflammatory and analgesic capacity.

Toosendanin OVA is an antigen-adjuvant conjugate of Toosendanin and ovalbumin (OVA). This conjugation enhances the production of antigen-specific antibodies in vaccine models by linking the antigen to a protein adjuvant. The conjugate does not alter protein folding or disrupt major epitopes, and it improves cross-presentation and the generation of antigen-specific T cells.

Toosendanin BSA is an antigen-adjuvant conjugate of Toosendanin and bovine serum albumin (BSA). The conjugation of the antigen with the protein adjuvant can enhance the production of antigen-specific antibodies in vaccine models. This conjugate does not affect protein folding or disrupt major epitopes and can increase cross-presentation and the generation of antigen-specific T cells.