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Results for "
tip 48
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Recombinant Protein1
TIP48/49-IN-1
T2063711807337-58-1
TIP48/49-IN-1 (Compound B) is an orally active, specific RUVBL1/2 ATPase inhibitor, with an IC50 of 59 nM for purified RUVBL1/2. It disrupts the DNA replication process, causing S phase arrest, induces apoptosis, inhibits tumor growth, and enhances the radiosensitivity of non-small cell lung cancer cells (NSCLC).
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