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By Target- Aurora Kinase
- PROTACs(1)
- Others(1)
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Results for "
thalidomide nh peg2 cooh
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products3
Thalidomide-NH-PEG2-COOH
Thalidomide-NH-PEG2-COOH
T400352412056-45-0
Thalidomide-NH-PEG2-COOH is a conjugate synthesized as an E3 ligase ligand-linker, incorporating the cereblon ligand from Thalidomide and a linker commonly used in [PROTAC] technology.
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JB300
T2042233038446-90-8
JB300 is a PROTAC-based compound that serves as a highly selective degrader of Aurora A, with a DC50 of 30 nM. It is utilized in cancer research. JB300 comprises the PROTAC target protein ligand MK-5108 [pink part], E3 ligase ligand Thalidomide-O-COOH [blue part], and PROTAC Linker Boc-NH-PEG2-C2-NH2 [black part]. The conjugate of the E3 ubiquitin ligase ligand and linker is Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc.
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Thalidomide-O-CH2-CO-NH-C2-PEG2-NH-Boc
T2042831957235-73-2
Thalidomide-O-COOH-NH2-C2-PEG2-NH-Boc is a conjugate combining an E3 ligase ligand with a linker, featuring a Thalidomide-based CEREBLON ligand and a PEG linker. It serves as a component in the synthesis of the PROTAC degrader JB300.
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