th-34

TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.

Odafosfamide ((S)-OBI-3424) is a highly selective prodrug bis-alkylating agent that is specifically activated by aldehyde-keto reductase 1C3 (AKR1C3), resulting in pronounced cytotoxicity toward tumor cell lines with elevated AKR1C3 expression, and it demonstrates significant antitumor activity in cancers such as liver cancer, non-small cell lung cancer, and leukemia, making it a targeted and mechanistically informative compound for precision oncology research.

ACTH (34-39), an adrenocorticotropic hormone fragment, is a peptide sequence comprising amino acids 34 to 39.