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tdp1 inhibitor 1

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  • Inhibitors & Agonists
    5
    TargetMol | Inhibitors_Agonists
TDP1 Inhibitor-1
T131092248702-80-7
TDP1 Inhibitor-1 is a potent inhibitor of Tyrosyl-DNA Phosphodiesterase 1 (TDP1) with an IC50 of 7 μM.
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6-8 weeks
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CID-7309015
T252511164457-99-1
CID-7309015 is a human tyrosyl-DNA phosphodiesterase 1 (TDP1) inhibitor, delayed death of the malarial parasite plasmid, the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1, ROR gamma transcriptiona
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6-8 weeks
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TDP1 Inhibitor-2
T62965859142-95-3
TDP1 Inhibitor-2 is a potent inhibitor of TDP1 (tyrosyl-DNA phosphodiesterase 1) (IC50: 99 nM) and inhibits SCAN1 (spinal cerebellar ataxia syndrome with axonal neuropathy) (IC50: 3.5 μM).
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6-8 weeks
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NSC109131
T6989321170-27-4
NSC109131 is an inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1).
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6-8 weeks
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TX-2552
T892342446767-14-0
TX-2552 is an orally effective inhibitor of tyrosyl-DNA phosphodiesterase 1 (TDP1), with an IC50 value of 0.62 μM. It enhances the cleavage activity of topotecan in mouse bone marrow cells and amplifies the antitumor effects of topotecan in Krebs-2 ascites tumor-bearing mice.
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10-14 weeks
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