tco-peg8-tco

TCO-PEG8-TCO, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.

TCO-PEG8-acid, a PEG-based linker for PROTACs, joins two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

TCO-PEG8-amine is a PEG-based linker for PROTACs that connects two essential ligands, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

TCO-PEG8-NHS ester is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

TCO-PEG8-TFP ester is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

(S)-TCO-PEG8-acid is a click chemistry PEG linker characterized by a terminal carboxylic acid (COOH) group. This terminal group reacts with primary amine groups to form stable amide bonds. As a PEG-based PROTAC linker, (S)-TCO-PEG8-acid is utilized in PROTAC synthesis. It is longer compared to (S)-TCO-PEG3-acid.